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  4. Recombinant Human Disintegrin and metalloproteinase domain-containing protein 29 (ADAM29), partial

Recombinant Human Disintegrin and metalloproteinase domain-containing protein 29 (ADAM29), partial

  • 中文名称：
    Recombinant Human Disintegrin and metalloproteinase domain-containing protein 29(ADAM29),partial,Yeast
  • 货号：
    CSB-YP891722HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Disintegrin and metalloproteinase domain-containing protein 29(ADAM29),partial,Yeast
  • 货号：
    CSB-EP891722HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Disintegrin and metalloproteinase domain-containing protein 29(ADAM29),partial,Yeast
  • 货号：
    CSB-EP891722HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Disintegrin and metalloproteinase domain-containing protein 29(ADAM29),partial,Yeast
  • 货号：
    CSB-BP891722HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Disintegrin and metalloproteinase domain-containing protein 29(ADAM29),partial,Yeast
  • 货号：
    CSB-MP891722HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ADAM29
  • Uniprot No.：
  • 别名：
    A disintegrin and metalloproteinase domain 29; ADA29_HUMAN; ADAM 29; ADAM metallopeptidase domain 29; ADAM29; Cancer/testis antigen 73; CT73; Disintegrin and metalloproteinase domain-containing protein 29; Metallaproteinase disintegrin (ADAM29); svph1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein.
  • 基因功能参考文献：
    1. Increased transcript expression of ADAM29 was observed in breast cancer tissues compared to normal ones. The expression of ADAM29 and its mutations in different domains significantly influenced proliferation, migration and invasion of breast cancer cells in vitro. PMID: 26977022
    2. PCMC expression of ADAM29, FLRT2, and SLC18A3 could be assessed as part of a routine screen to help identify individuals at risk of severe Obstructive sleep apnea in Asian populations PMID: 24732660
    3. mutated ADAM27 and ADAM7 genes could play a role in melanoma progression. PMID: 21618342
    4. quantification of LPL and ADAM29 gene expression is a strong prognostic indicator in CLL, providing better prognostic assessment than ZAP-70 in advanced stages of the disease PMID: 15802535
    5. Results support the use of LPL and ADAM29 gene expression associated to IGHV mutational status for predicting the clinical outcome of patients treated by oral fludarabine + cyclophosphamide and could be considered for treatment strategies. PMID: 19340428

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  • 相关疾病：
    Has been found to be frequently mutated in melanoma. ADAM7 mutations may play a role in melanoma progression and metastasis.
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Expressed specifically in testes.
  • 数据库链接：

    HGNC: 207

    OMIM: 604778

    KEGG: hsa:11086

    STRING: 9606.ENSP00000352177

    UniGene: Hs.126838