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  4. Recombinant Human Dipeptidyl peptidase 2 (DPP7)

Recombinant Human Dipeptidyl peptidase 2 (DPP7)

  • 中文名称：
    人DPP7重组蛋白
  • 货号：
    CSB-YP887041HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人DPP7重组蛋白
  • 货号：
    CSB-EP887041HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人DPP7重组蛋白
  • 货号：
    CSB-EP887041HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人DPP7重组蛋白
  • 货号：
    CSB-BP887041HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人DPP7重组蛋白
  • 货号：
    CSB-MP887041HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DPP7
  • Uniprot No.：
  • 别名：
    DPP7; DPP2; QPP; Dipeptidyl peptidase 2; EC 3.4.14.2; Dipeptidyl aminopeptidase II; Dipeptidyl peptidase 7; Dipeptidyl peptidase II; DPP II; Quiescent cell proline dipeptidase
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    26-492
  • 氨基酸序列
    APDPG FQERFFQQRL DHFNFERFGN KTFPQRFLVS DRFWVRGEGP IFFYTGNEGD VWAFANNSAF VAELAAERGA LLVFAEHRYY GKSLPFGAQS TQRGHTELLT VEQALADFAE LLRALRRDLG AQDAPAIAFG GSYGGMLSAY LRMKYPHLVA GALAASAPVL AVAGLGDSNQ FFRDVTADFE GQSPKCTQGV REAFRQIKDL FLQGAYDTVR WEFGTCQPLS DEKDLTQLFM FARNAFTVLA MMDYPYPTDF LGPLPANPVK VGCDRLLSEA QRITGLRALA GLVYNASGSE HCYDIYRLYH SCADPTGCGT GPDARAWDYQ ACTEINLTFA SNNVTDMFPD LPFTDELRQR YCLDTWGVWP RPDWLLTSFW GGDLRAASNI IFSNGNLDPW AGGGIRRNLS ASVIAVTIQG GAHHLDLRAS HPEDPASVVE ARKLEATIIG EWVKAARREQ QPALRGGPRL SL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays an important role in the degradation of some oligopeptides.
  • 基因功能参考文献：
    1. human DPP7 structures reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases PMID: 22952628
    2. The constitutive expression of dipeptidyl peptidase II mRNA in chronic lymphocytic leukemia was demonstrated. PMID: 20534982
    3. catalytic properties and inhibition of this proline-specific enzyme PMID: 12529175
    4. DPP II plays a minor role in the progression of malignant melanocytic lesions PMID: 18823758
    5. DPP2 is essential for maintaining lymphocytes and fibroblasts in G(0), and its inhibition results in apoptosis mediated by induction of c-Myc and p53. PMID: 19556882

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  • 亚细胞定位：
    Lysosome. Cytoplasmic vesicle. Secreted.
  • 蛋白家族：
    Peptidase S28 family
  • 组织特异性：
    Detected in seminal plasma (at protein level).
  • 数据库链接：

    HGNC: 14892

    OMIM: 610537

    KEGG: hsa:29952

    STRING: 9606.ENSP00000360635

    UniGene: Hs.37916