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  4. Recombinant Homeobox protein egl-5 (egl-5)

Recombinant Homeobox protein egl-5 (egl-5)

  • 货号：
    CSB-YP324634CXY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP324634CXY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP324634CXY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP324634CXY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP324634CXY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    egl-5
  • Uniprot No.：
  • 别名：
    egl-5; ceh-11; C08C3.1Homeobox protein egl-5; Egg-laying defective protein 5; Homeobox protein ceh-11
  • 种属：
    Caenorhabditis elegans
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-223
  • 氨基酸序列
    MNTSTSAFDF GSSTASSAAT STTSSQPDAN DHLSRLAAMT QGVGKEDPET SSTPSTEASL YPGISAAYMQ SYGWPQNYNY FGQPLGPATF PGWPQCYPNT AWPNYGELFA SSKKGRQTYQ RYQTSVLEAK FQQSSYVSKK QREELRLQTQ LTDRQIKIWF QNRRMKAKKE KQRVDDHTEH TPLLPANPPK GMGMDMDDEK KWQMAHWPPA AAHNPYQYPL CPP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Essential for the determination of specific neurons.
  • 基因功能参考文献：
    1. EGL-5 is required for subtype-specific circuit formation in both sensory neurons and interneurons. PMID: 26539892
    2. egl-5 plays an instructive role in male cell fate determination in the C. elegans somatic gonad. PMID: 20553900
    3. Data present an analysis of cis-regulatory elements in the Caenorhabditis elegans Hox gene egl-5, which is expressed in multiple tissues in the posterior region of the nematode. PMID: 15581880
    4. Mutating a CCAAT box in the proximal promoter of egl-5 leads to the derepression of egl-5, suggesting a direct role for the NFY complex in the regulation of egl-5. PMID: 17574230
    5. Expression of EGL-5 in the HSN motor neuron/PHB sensory neuron precursor but not in the PHB neuron suggests that EGL-5 specifies precursor fate. PMID: 18505863
    6. bar-1 beta-catenin and egl-5 homeobox genes play an important and conserved role in innate immune defense. PMID: 18981407
    7. The C. elegans Hox gene egl-5 is frequired for correct development of the hermaphrodite hindgut and for the response to rectal infection by Microbacterium nematophilum. PMID: 19232338

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Abd-B homeobox family
  • 数据库链接：

    KEGG: cel:CELE_C08C3.1

    STRING: 6239.C08C3.1b

    UniGene: Cel.19646