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  4. Recombinant Haloferax volcanii DNA double-strand break repair protein Mre11 (mre11)

Recombinant Haloferax volcanii DNA double-strand break repair protein Mre11 (mre11)

  • 货号：
    CSB-YP517111HTU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP517111HTU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP517111HTU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP517111HTU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP517111HTU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    mre11; HVO_0853; DNA double-strand break repair protein Mre11; EC 3.1.-.-
  • 种属：
    Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-441
  • 氨基酸序列
    MTRVIHTGDT HLGYQQYHSP ERRQDFLDAF ERVVADALDG DVDAVVHAGD LYHDRRPELP DLLGTLAALR RLDDAGIPFL AIVGNHESTR GGQWLDLFER LGLATRLGRD PHVVGGVAFY GLDHVPRSRR DELDYQFDPV DADRAVLVAH GLFTPFAHAD WETETVLAES NVDFDAVLLG DNHVPDTAEL DGTWVTYCGS TERASASERD PRGYNLVEFT PDAVDIRRRT LETRPFAFVE VDLAGDEGIE RVRQRVREFD LEDAVVIVEL RGEGETVTPA AVESFAVEEG ALVARVNDKR DIDDDGDLAT DVTFADPDDA VRERVREMGL SSAALDVDET VRASKVADSN VRDEVRERVE SLLSDDPDAF VAAERESDAE AEESESVEDA ADGEDAAAVE DTAETAAEAA TDTDTETTAD TDSETAADPA ASRDSSLGDF A
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. In polyploid organisms, the Rad50/Mre11 complex appears to restrain the repair of double-strand breaks by homologous recombination, allowing another pathway to act as the primary mode of repair.
  • 蛋白家族：
    MRE11/RAD32 family
  • 数据库链接：

    KEGG: hvo:HVO_0853

    STRING: 309800.HVO_0853