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  4. Recombinant Guinea pig Complement decay-accelerating factor (CD55)

Recombinant Guinea pig Complement decay-accelerating factor (CD55)

  • 货号：
    CSB-YP736710GU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP736710GU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP736710GU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP736710GU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP736710GU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    CD55; DAFComplement decay-accelerating factor; CD antigen CD55
  • 种属：
    Cavia porcellus (Guinea pig)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    32-507
  • 氨基酸序列
    DCGPLPVVP RAHPASASAG STSFPENTTV LYTCDQGFVK IPGKPDAVVC ISSRWTDIEE FCNRSCEVPP RLPYAILKSA YISKNYFPVD TVVEYECRPG YRKKYPIQSG KITCRDDLTW STPAEFCEKK QCPNPGELVN GNINVTTDLL LGSQIFFSCD PGYRLTGEAS AFCMIKGNAV GWSSSLPTCI KIICPEPPQI ENGRIVNEED TYEYRHVVTY ECNKGFVLTG KSHISCIVRD DVGEWSDPPP TCRVKSPPVI PPQKPTTTSA PGTTTTLPTQ KPTTVNTAGP EVPTTQRSTT VNVPGTKVPT TQRSTTVNVP GTEVPTTWKS TTVNVPAAGN RPDTRTTIKS TTASEEKDLA SGYRTFLYGV GVGVPVIVCS LGLGVYWWIH RTSGQYETYE NKESNVICHN LNESDATSEI TSSDKLKKTH VYKVDSFACG ASNHWLADIA KEDLRRDFSN AQNISSLLQV LGAAQTQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage.
  • 亚细胞定位：
    [Isoform 3]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 4]: Secreted.
  • 蛋白家族：
    Receptors of complement activation (RCA) family
  • 组织特异性：
    All the isoforms are widely expressed. GPI and TCS are the major forms, whereas SEC is minor and TCL is only present in trace levels.