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  4. Recombinant Feline panleukopenia virus Initiator protein NS1 (NS1)

Recombinant Feline panleukopenia virus Initiator protein NS1 (NS1)

  • 中文名称：
    Recombinant Feline panleukopenia virus Initiator protein NS1(NS1),Yeast
  • 货号：
    CSB-YP361823FAU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Feline panleukopenia virus Initiator protein NS1(NS1),Yeast
  • 货号：
    CSB-EP361823FAU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Feline panleukopenia virus Initiator protein NS1(NS1),Yeast
  • 货号：
    CSB-EP361823FAU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Feline panleukopenia virus Initiator protein NS1(NS1),Yeast
  • 货号：
    CSB-BP361823FAU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Feline panleukopenia virus Initiator protein NS1(NS1),Yeast
  • 货号：
    CSB-MP361823FAU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NS1
  • Uniprot No.：
  • 别名：
    NS1; Initiator protein NS1; NS1; EC 3.1.21.-; EC 3.6.4.12; NCVP1; Non-capsid protein NS-1; Non-structural protein 1; Non-structural protein NS1; Fragment
  • 种属：
    Feline panleukopenia virus (FPV)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-392
  • 氨基酸序列
    IQTKKEVSIK CTLRDLVSKR VTSPEDWMML QPDSYIEMMA QPGGENLLKN TLEICTLTLA RTKTAFELIL EKANNTKLTN FDLANSRTCQ IFRMHGWNWI KVCHAIACVL NRQGGKRNTV LFHGPASTGK SIIAQAIAQA VGNVGCYNAA NVNFPFNDCT NKNLIWIEEA GNFGQQVNQF KAICSGQTIR IDQKGKGSKQ IEPTPVIMTT NENITIVRIG CEERPEHTQP IRDRMLNIKL VCKLPGDFGL VDKEEWPLIC AWLVKHGYES TMANYTHHWG KVPEWDENWA EPKIQEGVNS PGCKDLETQA ASNPQSQDHV LTPLTPDVVD LALEPWSTPD TPIAETANQQ SNQLGVTHKD VQASPTWSEI EADLRAIFTS EQLEEDFRDD LD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Multifunctional protein which displays endonuclease and helicase activities required for initiating and directing viral DNA replication. Also plays a role in viral packaging and transactivation of several promoters. Binds site-specifically to 2-3 approximate tandem copies within the origins of replication (Ori), unwinds this hairpin region and nicks one DNA strand thereby initiating the rolling circle replication (RCR). Cooperatively binds Ori with host PIF and probably other host factors, which activate the nickase function of NS1. Becomes covalently attached to the 5' end of the nick and provides a 3'OH for priming DNA synthesis. The helicase activity unwinds DNA in a 3'-5' direction on the longer strand. Inhibits the host cell cycle during the G1/S transition, the S-phase, and the G2/M transition. These arrests may provide essential cellular factors for viral DNA replication. Promotes apoptosis in host cell.
  • 亚细胞定位：
    Host nucleus.
  • 蛋白家族：
    Parvoviruses non-capsid protein family