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  4. Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 3 (EBNA3), partial

Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 3 (EBNA3), partial

In Stock
  • 货号：
    CSB-EP319032EFA
  • 规格：
    ￥2328
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    EBNA3
  • Uniprot No.：
  • 别名：
    EBNA3; BLRF3-BERF1Epstein-Barr nuclear antigen 3; EBNA-3; EBV nuclear antigen 3; Epstein-Barr nuclear antigen 3A; EBNA-3A; EBV nuclear antigen 3A
  • 种属：
    Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
  • 蛋白长度：
    Partial
  • 来源：
    E.coli
  • 分子量：
    22.2 kDa
  • 表达区域：
    1-138aa
  • 氨基酸序列
    MDKDRPGPPALDDNMEEEVPSTSVVQEQVSAGDWENVLIELSDSSSEKEAEDAHLEPAQKGTKRKRVDHDAGGSAPARPMLPPQPDLPGREAILRRFPLDLRTLLQAIGAAATRIDTRAIDQFFGSQISNTEMYIMYA
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer，50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop.
  • 基因功能参考文献：
    1. the polycomb repressor complex is essential for EBNA3A-mediated repression of STK39 Findings in this study provide new insights into the regulation of cellular genes by the transcription factor EBNA3A. PMID: 29367247
    2. These results indicate that EBNA3 proteins interact with multiple RBP/CSL domains, but only N-terminal domain interactions are required for lymphoblastoid cell line growth. PMID: 21440926
    3. EBNA-3 plays a role in facilitating the ligand-dependent AhR activation process PMID: 16257957
  • 亚细胞定位：
    Host nucleus matrix. Note=Associated with the nuclear matrix.
  • 蛋白家族：
    Herpesviridae EBNA-3 family
  • 数据库链接：

    KEGG: vg:3783762