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  4. Recombinant Drosophila melanogaster U1 small nuclear ribonucleoprotein 70 kDa (snRNP-U1-70K)

Recombinant Drosophila melanogaster U1 small nuclear ribonucleoprotein 70 kDa (snRNP-U1-70K)

  • 货号：
    CSB-YP022325DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP022325DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP022325DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP022325DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP022325DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    snRNP-U1-70K
  • Uniprot No.：
  • 别名：
    snRNP-U1-70K; snRNP27D; snRNP70K; CG8749U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; U1-70K; snRNP70
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-448
  • 氨基酸序列
    MTQYLPPNLL ALFAAREPIP FMPPVDKLPH EKKSRGYLGV AKFMADFEDP KDTPLPKTVE TRQERLERRR REKAEQVAYK LEREIALWDP TEIKNATEDP FRTLFIARIN YDTSESKLRR EFEFYGPIKK IVLIHDQESG KPKGYAFIEY EHERDMHAAY KHADGKKIDS KRVLVDVERA RTVKGWLPRR LGGGLGGTRR GGNDVNIKHS GREDNERERE RYRLERERED REGPGRGGGS NGLDARPGRG FGAERRRSRS RERRDRERDR GRGAVASNGR SRSRSRERRK RRAGSRERYD EFDRRDRRDR ERERDRDRER EKKKKRSKSR ERESSRERRE RKRERRDRER GTGSGGDVKE RKPDFRDMDV IKIKEEPVDD GYPTFDYQNA TIKREIDDED EEKYRPPPAH HNMFSVPPPP ILGRGNASTN PNPDNGQQSS GDPSWWRQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Mediates the splicing of pre-mRNA by binding to the stem loop I region of U1-snRNA. Required during oogenesis for nurse cell chromatin dispersal.
  • 基因功能参考文献：
    1. SEX-LETHAL associates with U1 snRNP components in male exon skipping PMID: 12490553
    2. not essential for viability, nevertheless contribute to an essential U1 snRNP function. PMID: 15611175
  • 亚细胞定位：
    Nucleus speckle. Nucleus, nucleoplasm.
  • 数据库链接：

    KEGG: dme:Dmel_CG8749

    STRING: 7227.FBpp0303792

    UniGene: Dm.4728