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  4. Recombinant Drosophila melanogaster Tachykinins (Tk)

Recombinant Drosophila melanogaster Tachykinins (Tk)

  • 中文名称：
    黑腹果蝇Tk重组蛋白
  • 货号：
    CSB-YP892843DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Tk重组蛋白
  • 货号：
    CSB-EP892843DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Tk重组蛋白
  • 货号：
    CSB-EP892843DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Tk重组蛋白
  • 货号：
    CSB-BP892843DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Tk重组蛋白
  • 货号：
    CSB-MP892843DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Tk; CG14734; Tachykinins; dTk) [Cleaved into: Tachykinin-related peptide 1; TK-1; dTK-1; APTSSFIGMR-amide); Tachykinin-associated peptide 1; TAP1; DEEHDTSEGNWLGSGPDPLDYADEEADSSYAEN-amide); Tachykinin-related peptide 2; TK-2; dTK-2; APLAFVGLR-amide); Tachykinin-associated peptide 2; TAP2; FIPINNRLSDVLQSLEEERLRDSLLQDFFDRVAGRDGSAV-amide); Tachykinin-related peptide 3; TK-3; dTK-3; APTGFTGMR-amide); Tachykinin-associated peptide 3; TAP3; Brain peptide PALLAGDDDAEADEATELQQ); Tachykinin-related peptide 4; TK-4; dTK-4; APVNSFVGMR-amide); Tachykinin-associated peptide 4; TAP4; Brain peptide DVSHQHY); Tachykinin-associated peptide 5; TAP5; AALSDSYDLRGKQQRFADFNSKFVAVR-amide); Tachykinin-associated peptide 6; TAP6; Brain peptide SDLEGNGVGIGDDHEQALVHPWLYLWGE); Tachykinin-related peptide 5; TK-5; dTK-5; APNGFLGMR-amide)]
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    50-59
  • 氨基酸序列
    A PTSSFIGMR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Stimulates gut muscle contractions. Required for the response to the male sex pheromone CH503 which is transferred from males to females during mating and inhibits courtship behavior by other males. The Gr68a gustatory receptor is required for detection of the pheromone and Gr68a-expressing neurons in the male foreleg relay signals to the suboesophageal zone (SEZ) which leads to courtship suppression through release of tachykinin from a cluster of 8-10 neurons in the SEZ.
  • 基因功能参考文献：
    1. These results highlight a conserved role for Tachykinin signaling in regulating nociception. PMID: 26575288
    2. Study identified a small group of sexually dimorphic, FruM+ neurons that promote aggressiveness in Drosophila males but have no influence on male-female courtship behavior. These neurons enhance aggression, at least in part, through the release of a neuropeptide, Drosophila tachykinin. PMID: 24439378
    3. The control of DILP5 signaling in the renal tubules by Drosophila tachykinin peptide (DTK) and its receptor DTKR during desiccative, nutritional and oxidative stress, was investigated. PMID: 21572965
    4. The distribution of the Dtk transcript and peptides was analyzed by in situ hybridization and immunocytochemistry during postembryonic development of the central nervous system (CNS) of Drosophila. PMID: 12898611
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Tachykinin family
  • 组织特异性：
    Strong expression is seen in a group of 14 cells plus one isolated cell in the midgut of stage 17 embryos. Also expressed in a pair of medially located unidentified cells, just posterior to the brain, and in two lateral groups of cells that may be associa
  • 数据库链接：

    KEGG: dme:Dmel_CG14734

    STRING: 7227.FBpp0081962

    UniGene: Dm.3420