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  4. Recombinant Drosophila melanogaster Cathepsin L (Cp1)

Recombinant Drosophila melanogaster Cathepsin L (Cp1)

  • 中文名称：
    Recombinant Drosophila melanogaster Cathepsin L(Cp1),Yeast
  • 货号：
    CSB-YP822041DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Cathepsin L(Cp1),Yeast
  • 货号：
    CSB-EP822041DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Cathepsin L(Cp1),Yeast
  • 货号：
    CSB-EP822041DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Cathepsin L(Cp1),Yeast
  • 货号：
    CSB-BP822041DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Cathepsin L(Cp1),Yeast
  • 货号：
    CSB-MP822041DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cp1
  • Uniprot No.：
  • 别名：
    Cp1; fs(2)50Ca; CG6692Cathepsin L; EC 3.4.22.15; Cysteine proteinase 1) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain]
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    154-326
  • 氨基酸序列
    LPKSVDW RTKGAVTAVK DQGHCGSCWA FSSTGALEGQ HFRKSGVLVS LSEQNLVDCS TKYGNNGCNG GLMDNAFRYI KDNGGIDTEK SYPYEAIDDS CHFNKGTVGA TDRGFTDIPQ GDEKKMAEAV ATVGPVSVAI DASHESFQFY SEGVYNEPQC DAQNLDHGVL VVGFGT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Important for the overall degradation of proteins in lysosomes. Essential for adult male and female fertility. May play a role in digestion.
  • 基因功能参考文献：
    1. Data show that cysteine proteinase 1 (CP1) is expressed in air sac primordium (ASP) and knockdown of CP1 results in suppression of migratory and invasive behavior observed during ASP development. PMID: 26341534
    2. Data show the models of the tertiary structures of cathepsin L constructed by using homology modeling methods. PMID: 23256878
    3. Premature activation of the effector caspase, dcp1, resulted in a disappearance of filamentous actin, rather than the formation of actin bundles, suggesting that dcp-1 activity must be restrained in late oogenesis. PMID: 12885559
    4. Drosophila decapping protein 1, dDcp1, is a posterior group gene required for the transport of osk mRNA. PMID: 16678775
  • 亚细胞定位：
    Lysosome.
  • 蛋白家族：
    Peptidase C1 family
  • 组织特异性：
    In the embryo, predominantly expressed in the midgut. Also expressed in larval alimentary organs such as salivary gland and midgut including gastric caeca.
  • 数据库链接：

    KEGG: dme:Dmel_CG6692

    STRING: 7227.FBpp0086719

    UniGene: Dm.7400