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  4. Recombinant Drosophila melanogaster Casein kinase II subunit beta (CkIIbeta)

Recombinant Drosophila melanogaster Casein kinase II subunit beta (CkIIbeta)

  • 货号：
    CSB-YP006075DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP006075DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP006075DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP006075DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP006075DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CkIIbeta
  • Uniprot No.：
  • 别名：
    CkIIbeta; Cask-II-b; CG15224Casein kinase II subunit beta; CK II beta
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-235
  • 氨基酸序列
    MSSSEEVSWV TWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPNYRQAL DMILDLEPED ELEDNPLQSD MTEQAAEMLY GLIHARYILT NRGIAQMIEK YQTGDFGHCP RVYCESQPML PLGLSDIPGE AMVKTYCPKC IDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPT NQFVPRLYGF KIHSLAYQIQ LQAAANFKMP LRAQRGQPPK DEEPENNADT VPKRL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
  • 基因功能参考文献：
    1. Data (including data from studies using transgenic animals) suggest that catalytic activity of casein kinase 2 (CkIIa/CkIIb) is essential for oogenesis in this species; Jabba, a lipid droplet-associated protein and substrate for casein kinase 2, is essential in modulating ovarian lipid metabolism. (CkIIa = casein kinase II alpha subunit; CkIIb = casein kinase II beta subunit) PMID: 29326167
    2. Drosophila splicing factor P element Somatic Inhibitor (PSI) is phosphorylated at at least two different sites by at minimum two different kinases, casein kinase II (CK II) and tousled-like kinase (tlk). PMID: 23437125
    3. Coexpressing CK2alpha and CK2beta increases Smo accumulation and induces ectopic Hh target gene expression. PMID: 20876583
    4. Identification and characterization of proteins that interact with Drosophila melanogaster protein kinase CK2 PMID: 11827179
    5. ZFP47 is a new physiological partner and substrate of CK2. PMID: 11827180
    6. CK2(beta)tes encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 PMID: 11874456
    7. This study implicates a role for DmCK2beta in cell proliferation or cell survival during brain development. PMID: 12406573
    8. results reveal a potential mechanism for regulation of the dMi-2 enzyme and point toward CK2 phosphorylation as a common feature of CHD family ATPases PMID: 16223721
    9. The DmCK2beta transcription unit encodes for functionally non-redundant protein isoforms. PMID: 16530986

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  • 蛋白家族：
    Casein kinase 2 subunit beta family
  • 数据库链接：

    KEGG: dme:Dmel_CG15224

    STRING: 7227.FBpp0089135

    UniGene: Dm.142