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  4. Recombinant Danio rerio Retinoic acid receptor RXR-alpha-B (rxrab)

Recombinant Danio rerio Retinoic acid receptor RXR-alpha-B (rxrab)

  • 中文名称：
    斑马鱼rxrab重组蛋白
  • 货号：
    CSB-YP820870DIL
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    斑马鱼rxrab重组蛋白
  • 货号：
    CSB-EP820870DIL
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    斑马鱼rxrab重组蛋白
  • 货号：
    CSB-EP820870DIL-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    斑马鱼rxrab重组蛋白
  • 货号：
    CSB-BP820870DIL
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    斑马鱼rxrab重组蛋白
  • 货号：
    CSB-MP820870DIL
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    rxrab
  • Uniprot No.：
  • 别名：
    rxrab; nr2b1b; rxra; rxrg; Retinoic acid receptor RXR-alpha-B; Nuclear receptor subfamily 2 group B member 1-B; Retinoid X receptor alpha-B
  • 种属：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-379
  • 氨基酸序列
    MPVPEQKQTV QLSSPMNAVS SSEDIKPPLG LNGVMKVPAH RIGTLSLSLT KHICAICGDR SSGKHYGVYS CEGCKGFFKR TVRKDLTYTC RDNKDCMIDK RQRNRCQYCR YQKCLAMGMK REAVQEERQR AKERSEAEFG GCANEDMPVE KILEAELAVE PKTETYVEAN LSPSANSPND PVTNICQAAD KQLFTLVEWA KRIPHFSDLP LDDQVILLRA GWNELLIASF SHRSIAVKDG ILLATGLHVH RNSAHTAGVG AIFDRVLTEL VSKMRDMQMD KTELGCLRAI VLFNPDSKGL SNPSEVEALR ERVYASLEAY CKHKYPDQPG RFAKLLLRLP ALRSIGLKCL EHLFFFKLIG DTPIDTFLME MLEAPHQIT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 to regulate transcription. The high affinity ligand for rxrs is 9-cis retinoic acid. In the absence of ligand, the rar/rxr heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone deacetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and coactivators are recruited leading to transcriptional activation.
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Nuclear hormone receptor family, NR2 subfamily
  • 组织特异性：
    Uniform expression from the blastula to mid-gastrula stages. At 12 hours post-fertilization (hpf), expressed strongly in the tail and weakly elsewhere. At 24 hpf, weak expression in the forebrain, eyes and pharyngeal endoderm and continued expression in t
  • 数据库链接：

    KEGG: dre:793011

    STRING: 7955.ENSDARP00000004918

    UniGene: Dr.624