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  4. Recombinant Chicken Selenoprotein W (SEPW1)

Recombinant Chicken Selenoprotein W (SEPW1)

  • 中文名称：
    鸡SELENOW重组蛋白
  • 货号：
    CSB-YP021034CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡SELENOW重组蛋白
  • 货号：
    CSB-EP021034CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡SELENOW重组蛋白
  • 货号：
    CSB-EP021034CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡SELENOW重组蛋白
  • 货号：
    CSB-BP021034CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡SELENOW重组蛋白
  • 货号：
    CSB-MP021034CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SELENOW
  • Uniprot No.：
  • 别名：
    SELENOW; SELW; SEPW1; Selenoprotein W; SelW
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-85
  • 氨基酸序列
    MPLRVTVLYC GAUGYKPKYE RLRAELEKRF PGALEMRGQG TQEVTGWFEV TVGSRLVHSK KNGDGFVDTD AKLQRIVAAI QAALP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency.
  • 基因功能参考文献：
    1. As one important selenoprotein gene in skeletal muscles, SelW may play a role in the regulation of inflammation reaction in Se-deficiency myopathy. PMID: 25123462
    2. The SelW plays an important role in protection of splenic lymphocyte of birds from oxidative stress. PMID: 24515840
    3. Data suggest that optimal selenium (a dietary factor) promotes differentiation of embryonic myoblasts; up-regulation of SelW and up-regulation of myogenic regulatory factors (MRF4/MYF6; MRF5; myogenin/MYF4) are correlated upon Se treatment. PMID: 23054870
    4. Findings suggest that selenoprotein W (SelW) could reduce the oxidative damage induced by H(2)O(2) and had an important protective function in against oxidative damage. PMID: 22207219
    5. the expression of the SelW mRNA in the gastrointestinal tract tissues of chickens was found to correlate with the dietary Se concentrations, but not with the tissue Se contents. PMID: 21863323
    6. Data suggest that to effect optimal SelW gene expression, selenium (Se) must be provided in the diet and the media in adequate amounts and neither at excessive nor deficient levels. PMID: 21837452
    7. SelW might play an important role in the biochemical functions of Selenium in birds. PMID: 21132387

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    SelWTH family, Selenoprotein W subfamily
  • 组织特异性：
    Expressed ubiquitously with predominant expression in the pituitary, spinal cord, sciatic nerve, cerebral cortex, cerebral nuclei, thalamus, cerebellum, muscle, cartilage, trachea, gizzard and artery. Weakly expressed in pancreas, testis, ovary, kidney an
  • 数据库链接：

    KEGG: gga:100310814

    UniGene: Gga.20015