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  4. Recombinant Chicken Protein atonal homolog 7 (ATOH7)

Recombinant Chicken Protein atonal homolog 7 (ATOH7)

  • 货号：
    CSB-YP002307CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP002307CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP002307CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP002307CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP002307CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ATOH7
  • Uniprot No.：
  • 别名：
    ATOH7; ATH5Protein atonal homolog 7; Helix-loop-helix protein cATH-5; cATH5; Protein atonal homolog 5
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-151
  • 氨基酸序列
    KTCQSSHLD SGVESDIQCR SGSGCVVKCS TERMESAAKR RLAANARERR RMQGLNTAFD RLRKVVPQWG QDKKLSKYET LQMALSYIMA LTRILAEAER YSTEREWINL HCEHFHPESY HHYTGQKVAT DSDPYAQRIF SYHPEHFQIA N
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor that positively regulates the determination of retinal ganglion cell fate and formation of the optic nerve and retino-hypothalamic tract. Required for retinal circadian rhythm photoentrainment. During retinal neurogenesis, activates its own transcription, as well as the transcription of CHRNB3 and BRN3.
  • 基因功能参考文献：
    1. ath5 may lead to the photoreceptor pathway by inducing neuroD; takes part in retinal ganglion cell differentiation PMID: 15306648
    2. Inactivation of the ATH5 promoter in differentiated neurons is accompanied by replication-independent chromatin de-methylation PMID: 15342472
    3. ATH5 is selected by the beta3 promoter and coordinates the derepression and transcriptional activation of the beta3 gene during the specification of retinal ganglion cells PMID: 16260616
    4. In the mouse and chick retina, species-related variations in the chromatin-binding profiles of bHLH transcription factors correlate with distinct features of the Atoh7 promoters and underlie variations in the transcriptional rates of the Atoh7 genes. PMID: 19855019
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: gga:395388

    STRING: 9031.ENSGALP00000040088

    UniGene: Gga.199