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  4. Recombinant Chicken GATA-binding factor 3 (GATA3)

Recombinant Chicken GATA-binding factor 3 (GATA3)

  • 货号：
    CSB-YP009276CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP009276CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP009276CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP009276CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP009276CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    GATA3; GATA-binding factor 3; GATA-3; Transcription factor NF-E1c
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-444
  • 氨基酸序列
    MEVSTDQPRW VSHHHPAVLN GQHPDSHHPT LGHTYMDPTQ YPLAEEVDVL FNIDGQGNPV PPYYGNSVRA TVQRYPTAHH GSQVCRPPLL HGSLPWLDGS KALSSHHSAS PWNLSPFSKT SIHHSSPGPL SVYPPASSST LSAGHSSPHL FTFPPTPPKD VSPDPSISTP GSTGSTRQDE KECIKYQVSL ADTMKLESSH SRSSMASLGG ATSSAHHPIT TYPPYVPEYS SGLFPPSSLL GGSPTGFGCK SRPKARSSTE GRECVNCGAT STPLWRRDGT GHYLCNACGL YHKMNGQNRP LIKPKRRLSA ARRAGTSCAN CQTTTTTLWR RNANGDPVCN ACGLYYKLHN INRPLTMKKE GIQTRNRKMS SKSKKCKKVH DNLEDFPKSS SFNPAALSRH MSSISHISPF SHSSHMLTTP TPMHPPSSLS FGPHHPSSMV TAMG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes.
  • 基因功能参考文献：
    1. data establish Gata2 and Gata3 as essential members of the transcription factor network controlling sympathetic neuron development. PMID: 15329349
    2. GATA3 impacts WNT signaling in this region of the sensory macula. PMID: 19924793
    3. Gata3 was mainly expressed in the developing sensory epithelia, reflecting the importance of this factor in the sensory-neural development of the inner ear. PMID: 17103399
    4. During regeneration in the avian utricle, regionalized expression of GATA3 is maintained after severe hair cell lesions and after transplantation of the sensory epithelium onto a chemically defined substrate. PMID: 17154269
    5. Our results suggest that Gata3 may be specifically involved in the differentiation of auditory ganglion neurons during embryogenesis. PMID: 19673002

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  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expressed only in definitive (adult) erythrocytes within the red cell lineage, and is also abundantly expressed in T-lymphocytes and brain.
  • 数据库链接：

    KEGG: gga:419106

    STRING: 9031.ENSGALP00000010868

    UniGene: Gga.744