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Recombinant Bovine Protein IMPACT (IMPACT)

  • 中文名称：
    牛IMPACT重组蛋白
  • 货号：
    CSB-YP011696BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛IMPACT重组蛋白
  • 货号：
    CSB-EP011696BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛IMPACT重组蛋白
  • 货号：
    CSB-EP011696BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛IMPACT重组蛋白
  • 货号：
    CSB-BP011696BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛IMPACT重组蛋白
  • 货号：
    CSB-MP011696BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    IMPACT
  • Uniprot No.：
  • 别名：
    IMPACT; Protein IMPACT; Imprinted and ancient gene protein homolog
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-318
  • 氨基酸序列
    MAEGDTGSDQ RQNEEIEAMA AIYGEEWCVI DDCAKIFCIR ISDDIDDPKW TLCLQVMLPN EYPGTAPPIY QLNAPWLKGQ ERADLSNSLE EIYIQNIGES ILYLWVEKIR DVLIQKSQMT EPGPDVKKKT EEEDVECEDD LVLACQPENQ VKTLDFDVSE NRTEIEELPP IDHGIPITDR RSTFQAHLAP VVCPKQVKMV LAKLYENKKI ASATHNIYAY RIYCEDKQTF LQDCEDDGET AAGGRLLHLM EILNVRDVMV VVSRWYGGVL LGPDRFKHIN NCARNILVEK NYTNSPEESS KALGKNKKVR KDKKRSEH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation. Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its inhibitory action on EIF2AK4/GCN2, plays a role in differentiation of neuronal cells by stimulating neurite outgrowth.
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    IMPACT family
  • 数据库链接：

    KEGG: bta:517248

    STRING: 9913.ENSBTAP00000045263

    UniGene: Bt.3093