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  4. Recombinant Bovine Prostaglandin E synthase 2 (PTGES2)

Recombinant Bovine Prostaglandin E synthase 2 (PTGES2)

  • 货号：
    CSB-YP018977BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP018977BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP018977BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP018977BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP018977BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    PTGES2; PGES2Prostaglandin E synthase 2; EC 5.3.99.3; Membrane-associated prostaglandin E synthase-2; mPGE synthase-2; Microsomal prostaglandin E synthase 2; mPGES-2) [Cleaved into: Prostaglandin E synthase 2 truncated form]
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-79
  • 氨基酸序列
    ERSATQLSLS SRLQLTLYQY KTAEIKFSSY RKVPILVAQE GESLQQLNDS SVIISALKTY LVSGQPLADI ITYYPAMKA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (in vitro). The biological function and the GSH-dependent property of PTGES2 is still under debate. In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA).
  • 亚细胞定位：
    Microsome membrane; Single-pass membrane protein.; [Prostaglandin E synthase 2 truncated form]: Cytoplasm.
  • 蛋白家族：
    GST superfamily
  • 组织特异性：
    Detected in heart (at protein level). Widely expressed. Expressed in heart > kidney > muscle > testis > endometrium = ovary > myometrium = spleen = lung. In endometrium, it is mainly expressed in luminal epithelial cells followed by glandular epithelial c
  • 数据库链接：

    KEGG: bta:493639

    STRING: 9913.ENSBTAP00000021584

    UniGene: Bt.34207