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  4. Recombinant Bovine Glutathione peroxidase 1 (GPX1)

Recombinant Bovine Glutathione peroxidase 1 (GPX1)

  • 货号：
    CSB-YP009866BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP009866BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP009866BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP009866BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP009866BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    GPX1Glutathione peroxidase 1; GPx-1; GSHPx-1; EC 1.11.1.9; Cellular glutathione peroxidase
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-205
  • 氨基酸序列
    MCAAQRSAAA LAAAAPRTVY AFSARPLAGG EPFNLSSLRG KVLLIENVAS LUGTTVRDYT QMNDLQRRLG PRGLVVLGFP CNQFGHQENA KNEEILNCLK YVRPGGGFEP NFMLFEKCEV NGEKAHPLFA FLREVLPTPS DDATALMTDP KFITWSPVCR NDVSWNFEKF LVGPDGVPVR RYSRRFLTID IEPDIETLLS QGASA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Protects the hemoglobin in erythrocytes from oxidative breakdown. In platelets, plays a crucial role of glutathione peroxidase in the arachidonic acid metabolism.
  • 基因功能参考文献：
    1. Studied the importance of selenium in bovine female reproductive function. Gene expression analysis revealed selenoprotein gene GPX1 was significantly up-regulated in large healthy follicles. PMID: 25362850
    2. did not find any significant inhibition of bovine GPx-1 by (S)- or (R)-misonidazole. PMID: 24375829
    3. Data indicate a positive correlation between GSH-Px activity and serum selenium concentration for all the cows analysed together. PMID: 22089971
    4. Data indicate mRNA level and activity of GPx1 are regulated by level of selenium supplied to hepatocytes. PMID: 19269156
    5. homocysteine decreases GPx1 activity by altering the translational mechanism PMID: 15734734
    6. glutathione peroxidase-1 activity is decreased by aminoglycosides through interference with selenocysteine incorporation PMID: 16354666

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Glutathione peroxidase family
  • 数据库链接：

    KEGG: bta:281209

    UniGene: Bt.4317