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  4. Recombinant Bovine Alpha-1-acid glycoprotein (ORM1)

Recombinant Bovine Alpha-1-acid glycoprotein (ORM1)

  • 货号：
    CSB-YP660972BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP660972BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP660972BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP660972BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP660972BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ORM1
  • Uniprot No.：
  • 别名：
    ORM1; AGPAlpha-1-acid glycoprotein; Orosomucoid; OMD
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    19-202
  • 氨基酸序列
    QS PECANLMTVA PITNATMDLL SGKWFYIGSA FRNPEYNKSA RAIQAAFFYL EPRHAEDKLI TREYQTIEDK CVYNCSFIKI YRQNGTLSKV ESDREHFVDL LLSKHFRTFM LAASWNGTKN VGVSFYADKP EVTQEQKKEF LDVIKCIGIQ ESEIIYTDEK KDACGPLEKQ HEEERKKETE AS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Appears to function in modulating the activity of the immune system during the acute-phase reaction.
  • 基因功能参考文献：
    1. The presence of lipopolysaccharide binding protein (LBP) and alpha1-acid glycoprotein (AGP) was demonstrated in all seven adipose tissue depots. Expression of AGP and LBP suggests that they may have roles as local and systemic inflammatory adipokines. PMID: 25542063
    2. results provide evidence that locally produced alpha-1 acid glycoprotein may be involved in protecting sperm from phagocytosis by polymorphonuclear neutrophils in the bovine oviduct PMID: 24931131
    3. Studied the regulation and immune function of AGP in cultured bovine oviduct epithelial cells. PMID: 25123565
    4. As in human AGP and several other lipocalins, a temperature-induced molten globule state has been observed in the denaturation pathway of bovine AGP. PMID: 24530968
    5. In the mitochondrial membrane, both AGP and MLQ proteins are almost quantitatively bound to ATP synthase. PMID: 17575325
    6. Alpha1-acid glycoprotein isoforms that can be detected in bovine milk are reported. PMID: 17692138
    7. study provides evidence that the expression of CD18 was downregulated by the plasma glycoforms of alpha-1 acid glycoprotein and inhibited the chemotaxis of monocytes PMID: 18577362

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Calycin superfamily, Lipocalin family
  • 数据库链接：

    KEGG: bta:497200

    STRING: 9913.ENSBTAP00000022991

    UniGene: Bt.49064