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luxS Antibody

  • 货号：
    CSB-PA541717HA01ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: luxS antibody at 2µg/ml + DH5a whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 20 kDa
      Observed band size: 20 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Escherichia coli luxS Polyclonal antibody
  • Uniprot No.：
    P45578
  • 基因名：
    luxS
  • 别名：
    luxS antibody; ygaG antibody; b2687 antibody; JW2662 antibody; S-ribosylhomocysteine lyase antibody; EC 4.4.1.21 antibody; AI-2 synthesis protein antibody; Autoinducer-2 production protein LuxS antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Escherichia coli
  • 免疫原：
    Recombinant Escherichia coli S-ribosylhomocysteine lyase protein (2-171AA)
  • 免疫原种属：
    Escherichia coli
  • 标记方式：
    Non-conjugated

    本页面中的产品，luxS Antibody (CSB-PA541717HA01ENV)，的标记方式是Non-conjugated。对于luxS Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA541717HB01ENV luxS Antibody, HRP conjugated ELISA
    FITC CSB-PA541717HC01ENV luxS Antibody, FITC conjugated
    Biotin CSB-PA541717HD01ENV luxS Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
  • 基因功能参考文献：
    1. study demonstrated that luxS affects the expression of flagella and Stx2e toxin, 2 important STEC virulence factors PMID: 24848979
    2. LuxS contributes to virulence in avian pathogenic Escherichia coli O78:K80:H9. PMID: 23958403
    3. Proteomic profiling of luxS mutants showed only a few proteins were differentially expressed and those that were altered suggested a metabolic rather than communication role for the E. coli luxS gene product. PMID: 23651217
    4. Deletion of the luxS gene reduced the bacterial virulence by 31.5-fold in ducklings. PMID: 23046700
    5. Polyphosphate degradation in stationary phase triggers biofilm formation via LuxS quorum sensing system in Escherichia coli. PMID: 23226268
    6. Pfs and LuxS synthesize AI-2 in vitro from S-ribosylhomocysteine. PMID: 23236852
    7. luxS deletion significantly increases swimming motility and flagella synthesis in Escherichia coli K12. PMID: 20875395
    8. These data are consistent with the function of LuxS as an important metabolic enzyme but appear not to support the role of AI-2 as a true signal molecule for E. coli W3110 under the investigated conditions. PMID: 16321939
    9. The active form of LuxS contains a metal-bound water and a thiolate ion at Cys-83, consistent with the proposed roles of the metal ion (Lewis acid) and Cys-83 (general acid/base) during catalysis. PMID: 17014073

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  • 蛋白家族：
    LuxS family
  • 数据库链接：

    KEGG: ecj:JW2662

    STRING: 316385.ECDH10B_2854