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XPO6 Antibody

  • 货号:
    CSB-PA842747ESR1HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA842747ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA842747ESR1HU at dilution of 1:100
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) XPO6 Polyclonal antibody
  • Uniprot No.:
    Q96QU8
  • 基因名:
    XPO6
  • 别名:
    Exp6 antibody; Exportin 6 antibody; Exportin-6 antibody; RAN binding protein 20 antibody; Ran-binding protein 20 antibody; RANBP20 antibody; xpo6 antibody; XPO6_HUMAN antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Exportin-6 protein (290-530AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen Affinity Purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IHC
  • 推荐稀释比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Mediates the nuclear export of actin and profilin-actin complexes in somatic cells.
  • 基因功能参考文献:
    1. These results shed light on the crucial role of LN1 in quiescence and differentiation and how defects in the LN1/PI3K/XPO6/N-actin axis explain the loss of tissue homeostasis and growth control that contributes to malignant progression. PMID: 28591581
    2. potential prognostic biomarker for predicting prostate cancer recurrence [meta-analysis] PMID: 26709895
    3. identify exportin 6 (Exp6) as a novel family member from higher eukaryotes and show that it mediates nuclear export of profilin.actin complexes PMID: 14592989
  • 亚细胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    Exportin family
  • 数据库链接:

    HGNC: 19733

    OMIM: 608411

    KEGG: hsa:23214

    STRING: 9606.ENSP00000302790

    UniGene: Hs.460468