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UBXN11 Antibody

  • 中文名称：
    UBXN11兔多克隆抗体
  • 货号：
    CSB-PA070242
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q5T124
  • 基因名：
    UBXN11
  • 别名：
    COA 1 antibody; colorectal tumor associated antigen 1 antibody; Colorectal tumor associated antigen COA 1 antibody; Colorectal tumor-associated antigen COA-1 antibody; PP2243 antibody; SOC antibody; SOCI antibody; Socius antibody; UBX domain containing 5 antibody; UBX domain containing protein 11 antibody; UBX domain containing protein 5 antibody; UBX domain-containing protein 11 antibody; UBX domain-containing protein 5 antibody; UBX11_HUMAN antibody; UBXD 5 antibody; UBXN11 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Socius.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13.
  • 基因功能参考文献：
    1. Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers PMID: 11940653
    2. Both CD4+ and CD8+ T-cell responses against COA-1 can occur in colorectal cancer patients with metastatic disease PMID: 18974390
    3. The rat homolog of UBXD5 promotes RhoA activation through G12/13 heterotrimeric G proteins PMID: 16202387
  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 数据库链接：

    HGNC: 30600

    OMIM: 609151

    KEGG: hsa:91544

    STRING: 9606.ENSP00000363338

    UniGene: Hs.145061