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  4. TXLNA Antibody

TXLNA Antibody

  • 中文名称：
    TXLNA兔多克隆抗体
  • 货号：
    CSB-PA843964
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA843964(TXLNA Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: K562 cells, 293T cells, Primary antibody: CSB-PA843964(TXLNA Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

产品详情

  • Uniprot No.：
    P40222
  • 基因名：
    TXLNA
  • 别名：
    Alpha-taxilin antibody; DKFZp451J0118 antibody; IL 14 antibody; IL14 antibody; interleukin 14 antibody; MGC11887 antibody; MGC118870 antibody; MGC118871 antibody; RP4-622L5.4 antibody; Taxilin alpha antibody; TXLN antibody; TXLNA antibody; TXLNA_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human TXLNA
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
  • 基因功能参考文献：
    1. intrathyroidal production of IL-14 and IL-16 associated with the pathogenesis of autoimmune thyroid disease PMID: 25940130
    2. Silencing of alpha-taxilin expression leads to increased release of infectious hepatitis C virus particles. PMID: 26527738
    3. alpha-taxilin interacts with SNX4 and plays a role in the recycling pathway of TfnR. PMID: 24690921
    4. alpha-taxilin plays an essential role for release of HBV-DNA containing particles. PMID: 23816704
    5. Alpha-taxilin is localized on intracellular components in a syntaxin-independent manner and that the alpha-taxilin-containing intracellular components are associated with the microtubule cytoskeleton. PMID: 22785156
    6. Increased alpha-taxilin protein expression is associated with the metastatic and invasive potential of renal cell cancer. PMID: 21551945
    7. alpha-taxilin may be involved in cell proliferation of hepatocellular carcinoma(HCC), and its expression can be a marker of malignant potential of HCC. PMID: 21042709
    8. identification of isoforms; interaction with syntaxin [alpha-taxilin] PMID: 15184072
    9. role for IL-14alpha (Txln gene product)in the development of both autoimmunity and lymphomagenesis PMID: 17015757
    10. increases in IL-14 transcript levels may play a role in alloantibody formation after renal transplantation PMID: 18645499
    11. IL-14a is important in the pathophysiology of Sjogren's disease PMID: 19038581
    12. analysis of a novel monoclonal antibody against interleukin-14alpha PMID: 19663695

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  • 蛋白家族：
    Taxilin family
  • 组织特异性：
    Ubiquitous, with much higher expression in heart, kidney, liver and pancreas.
  • 数据库链接：

    HGNC: 30685

    OMIM: 608676

    KEGG: hsa:200081

    STRING: 9606.ENSP00000362711

    UniGene: Hs.17987