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  4. Recombinant Human Alpha-taxilin (TXLNA)

Recombinant Human Alpha-taxilin (TXLNA)

  • 中文名称：
    人TXLNA重组蛋白
  • 货号：
    CSB-YP025363HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人TXLNA重组蛋白
  • 货号：
    CSB-EP025363HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人TXLNA重组蛋白
  • 货号：
    CSB-EP025363HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人TXLNA重组蛋白
  • 货号：
    CSB-BP025363HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人TXLNA重组蛋白
  • 货号：
    CSB-MP025363HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TXLNA
  • Uniprot No.：
  • 别名：
    Alpha-taxilin; DKFZp451J0118; IL 14; IL14; interleukin 14; MGC11887; MGC118870; MGC118871; RP4-622L5.4; Taxilin alpha; TXLN; TXLNA; TXLNA_HUMAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-546
  • 氨基酸序列
    MKNQDKKNGA AKQSNPKSSP GQPEAGPEGA QERPSQAAPA VEAEGPGSSQ APRKPEGAQA RTAQSGALRD VSEELSRQLE DILSTYCVDN NQGGPGEDGA QGEPAEPEDA EKSRTYVARN GEPEPTPVVN GEKEPSKGDP NTEEIRQSDE VGDRDHRRPQ EKKKAKGLGK EITLLMQTLN TLSTPEEKLA ALCKKYAELL EEHRNSQKQM KLLQKKQSQL VQEKDHLRGE HSKAVLARSK LESLCRELQR HNRSLKEEGV QRAREEEEKR KEVTSHFQVT LNDIQLQMEQ HNERNSKLRQ ENMELAERLK KLIEQYELRE EHIDKVFKHK DLQQQLVDAK LQQAQEMLKE AEERHQREKD FLLKEAVESQ RMCELMKQQE THLKQQLALY TEKFEEFQNT LSKSSEVFTT FKQEMEKMTK KIKKLEKETT MYRSRWESSN KALLEMAEEK TVRDKELEGL QVKIQRLEKL CRALQTERND LNKRVQDLSA GGQGSLTDSG PERRPEGPGA QAPSSPRVTE APCYPGAPST EASGQTGPQE PTSARA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
  • 基因功能参考文献：
    1. intrathyroidal production of IL-14 and IL-16 associated with the pathogenesis of autoimmune thyroid disease PMID: 25940130
    2. Silencing of alpha-taxilin expression leads to increased release of infectious hepatitis C virus particles. PMID: 26527738
    3. alpha-taxilin interacts with SNX4 and plays a role in the recycling pathway of TfnR. PMID: 24690921
    4. alpha-taxilin plays an essential role for release of HBV-DNA containing particles. PMID: 23816704
    5. Alpha-taxilin is localized on intracellular components in a syntaxin-independent manner and that the alpha-taxilin-containing intracellular components are associated with the microtubule cytoskeleton. PMID: 22785156
    6. Increased alpha-taxilin protein expression is associated with the metastatic and invasive potential of renal cell cancer. PMID: 21551945
    7. alpha-taxilin may be involved in cell proliferation of hepatocellular carcinoma(HCC), and its expression can be a marker of malignant potential of HCC. PMID: 21042709
    8. identification of isoforms; interaction with syntaxin [alpha-taxilin] PMID: 15184072
    9. role for IL-14alpha (Txln gene product)in the development of both autoimmunity and lymphomagenesis PMID: 17015757
    10. increases in IL-14 transcript levels may play a role in alloantibody formation after renal transplantation PMID: 18645499
    11. IL-14a is important in the pathophysiology of Sjogren's disease PMID: 19038581
    12. analysis of a novel monoclonal antibody against interleukin-14alpha PMID: 19663695

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  • 蛋白家族：
    Taxilin family
  • 组织特异性：
    Ubiquitous, with much higher expression in heart, kidney, liver and pancreas.
  • 数据库链接：

    HGNC: 30685

    OMIM: 608676

    KEGG: hsa:200081

    STRING: 9606.ENSP00000362711

    UniGene: Hs.17987