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TFDP2 Antibody

  • 货号：
    CSB-PA623906LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse heart tissue, Hela whole cell lysate
      All lanes: TFDP2 antibody at 3.2μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000000 dilution
      Predicted band size: 50, 41, 42, 43, 40, 35, 47 kDa
      Observed band size: 50 kDa
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA623906LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA623906LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TFDP2 Polyclonal antibody
  • Uniprot No.：
    Q14188
  • 基因名：
  • 别名：
    DP2 antibody; E2F dimerization partner 2 antibody; Tfdp2 antibody; TFDP2_HUMAN antibody; Transcription factor Dp 2 antibody; Transcription factor Dp-2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Transcription factor Dp-2 protein (344-386AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TFDP2 Antibody (CSB-PA623906LA01HU)，的标记方式是Non-conjugated。对于TFDP2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA623906LB01HU TFDP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA623906LC01HU TFDP2 Antibody, FITC conjugated
    Biotin CSB-PA623906LD01HU TFDP2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters.
  • 基因功能参考文献：
    1. GAB2, GSPT1, TFDP2 and ZFPM1 are four new susceptibility loci for testicular germ cell tumor. PMID: 26503584
    2. DP2 is expressed by the bronchial epithelium, and its activation drives epithelial differentiation, suggesting that in addition to its well-characterized role in inflammatory cell migration, DP2 might contribute to airway remodeling in asthmatic patients. PMID: 25312757
    3. This study demonstrates translation from an internal methionine. PMID: 8755520
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    E2F/DP family
  • 组织特异性：
    High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.
  • 数据库链接：

    HGNC: 11751

    OMIM: 602160

    KEGG: hsa:7029

    STRING: 9606.ENSP00000420616

    UniGene: Hs.379018