TECPR1 Antibody
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货号:CSB-PA773603LA01HU
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规格:¥440
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促销:
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图片:
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) TECPR1 Polyclonal antibody
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Uniprot No.:Q7Z6L1
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基因名:TECPR1
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别名:2210010N04Rik antibody; DKFZP434B0335 antibody; FLJ23419 antibody; FLJ90593 antibody; KIAA1358 antibody; MGC124730 antibody; mKIAA1358 antibody; RGD1306873 antibody; TCPR1_HUMAN antibody; Tecpr1 antibody; tectonin beta propeller repeat containing 1 antibody; Tectonin beta-propeller repeat-containing protein 1 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Tectonin beta-propeller repeat-containing protein 1 protein (199-487AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,TECPR1 Antibody (CSB-PA773603LA01HU),的标记方式是Non-conjugated。对于TECPR1 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, IHC, IF
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推荐稀释比:
Application Recommended Dilution IHC 1:20-1:200 IF 1:50-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
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基因功能参考文献:
- The concerted interactions among TECPR1, Atg12-Atg5, and PtdIns(3)P provide the fusion specificity between autophagosomes and lysosomes and that the assembly of this complex initiates the autophagosome maturation process. PMID: 22342342
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亚细胞定位:Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes.
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蛋白家族:TECPR1 family
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数据库链接:
HGNC: 22214
OMIM: 614781
KEGG: hsa:25851
STRING: 9606.ENSP00000404923
UniGene: Hs.592281
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