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SPATA16 Antibody

  • 货号：
    CSB-PA871597LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA871597LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA871597LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SPATA16 Polyclonal antibody
  • Uniprot No.：
    Q9BXB7
  • 基因名：
    SPATA16
  • 别名：
    NYD SP12 antibody; NYD-SP12 antibody; NYDSP12 antibody; SPATA16 antibody; Spermatogenesis associated 16 antibody; Spermatogenesis-associated protein 16 antibody; SPGF6 antibody; SPT16_HUMAN antibody; Testis development protein antibody; Testis development protein NYD-SP12 antibody; Testis specific Golgi protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Spermatogenesis-associated protein 16 protein (238-475AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SPATA16 Antibody (CSB-PA871597LA01HU)，的标记方式是Non-conjugated。对于SPATA16 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA871597LB01HU SPATA16 Antibody, HRP conjugated ELISA
    FITC CSB-PA871597LC01HU SPATA16 Antibody, FITC conjugated
    Biotin CSB-PA871597LD01HU SPATA16 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion.
  • 基因功能参考文献：
    1. This study demonstrates that Spata16 is indispensable for male fertility in mice, as well as in humans. PMID: 29065458
    2. Mutation of SPATA16 is associated with globozoospermia. PMID: 27086357
    3. Case Report: report of a pregnancy obtained in a man with homozygous SPATA16 mutated globozoospermia. PMID: 24825417
    4. results suggest that NYD-SP12 is involved in spermatogenesis, and that NYD-SP12-encoded protein might function in the Golgi apparatus PMID: 12529416
    5. study demonstrated NYD-SP12 protein was involved in the formation of the acrosome during spermatogenesis PMID: 16372119
    6. Results indicate that NYD-SP12 evolves rapidly in both the human and the chimpanzee lineages, which is likely caused by Darwinian positive selection and/or sexual selection. PMID: 17665087
    7. consanguineous family with three affected brothers, in whom we have identified a homozygous mutation in the spermatogenesis-specific gene SPATA16. This is the first example of a nonsyndromic male infertility condition caused by an autosomal gene defect. PMID: 17847006

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  • 相关疾病：
    Spermatogenic failure 6 (SPGF6)
  • 亚细胞定位：
    Golgi apparatus. Note=Localized to the perinuclear region.
  • 蛋白家族：
    SPATA16 family
  • 组织特异性：
    Expressed in testis.
  • 数据库链接：

    HGNC: 29935

    OMIM: 102530

    KEGG: hsa:83893

    STRING: 9606.ENSP00000341765

    UniGene: Hs.444236