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  4. RUFY1 Antibody

RUFY1 Antibody

  • 货号：
    CSB-PA060182
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q96T51
  • 基因名：
  • 别名：
    3000002E04Rik antibody; FLJ22251 antibody; FYVE finger protein EIP1 antibody; FYVE-finger protein EIP1 antibody; La binding protein 1 antibody; La-binding protein 1 antibody; OTTHUMP00000161521 antibody; Rab4 interacting protein antibody; Rab4-interacting protein antibody; RABIP4 antibody; RUFY1 antibody; RUFY1_HUMAN antibody; RUN and FYVE domain containing 1 antibody; RUN and FYVE domain-containing protein 1 antibody; RUN and FYVE domains containing protein 1 antibody; ZFYVE12 antibody; Zinc finger FYVE domain containing protein 12 antibody; Zinc finger FYVE domain-containing protein 12 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human RUFY1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
  • 基因功能参考文献：
    1. RUFY1 may be involved in endolysosomal transport-a process known to be important to development of early onset AD. PMID: 28738127
    2. Data indicate that RUN and FYVE domain protein Rabip4'(RUFY1) interacts specifically and directly with adaptor protein complex AP-3. PMID: 23144738
    3. These findings suggest that Rab14 and Rab4 act sequentially, together with RUFY1. PMID: 20534812
    4. interaction with tyrosine kinase Etk PMID: 11877430
  • 亚细胞定位：
    Cytoplasm. Early endosome membrane; Peripheral membrane protein.
  • 组织特异性：
    Broadly expressed, with highest levels in lung, testis, kidney and brain.
  • 数据库链接：

    HGNC: 19760

    OMIM: 610327

    KEGG: hsa:80230

    STRING: 9606.ENSP00000325594

    UniGene: Hs.306769