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RPLP1 Antibody

  • 货号：
    CSB-PA914244
  • 规格：
    ￥1100
  • 图片：
    • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human normal liver tissue, hepg2 cells, Primary antibody: CSB-PA914244(RPLP1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

产品详情

  • Uniprot No.：
    P05386
  • 基因名：
    RPLP1
  • 别名：
    60S acidic ribosomal protein P1 antibody; RLA1_HUMAN antibody; Rplp1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human RPLP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays an important role in the elongation step of protein synthesis.
  • 基因功能参考文献：
    1. Data show that ricin A-chain (RTA) interacts directly with recombinant P1-P2 dimer, indicating the importance of P1 and P2 in enabling RTA to bind and depurinate ribosomes. PMID: 22909382
    2. the P1 and P2 proteins are not actively transported into the nucleus compartment, remaining predominantly in the cytoplasm (the perinuclear compartment). PMID: 12479870
    3. Data indicate that P1/P2 proteins modulate cytoplasmic translation by influencing the interaction between subunits, thereby regulating the rate of cell proliferation. PMID: 18422483
    4. These results support the hypothesis that at least some of the changes in the profile of newly synthesized proteins detected in cells deprived of P1 and P2 proteins might be due to an effect on the efficiency of cap-independent translation. PMID: 18675807
  • 蛋白家族：
    Eukaryotic ribosomal protein P1/P2 family
  • 数据库链接：

    HGNC: 10372

    OMIM: 180520

    KEGG: hsa:6176

    STRING: 9606.ENSP00000346037

    UniGene: Hs.356502