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Prothoracicotropic hormone Antibody

  • 货号：
    CSB-PA324609LA01BTT
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Bombyx mori N/A Polyclonal antibody
  • Uniprot No.：
    P17219
  • 基因名：
    N/A
  • 别名：
    antibody; Prothoracicotropic hormone antibody; PTTH) [Cleaved into: P2K; P6K; Prothoracicotropic hormone] antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Bombyx mori
  • 免疫原：
    Recombinant Bombyx mori Prothoracicotropic hormone protein (116-224AA)
  • 免疫原种属：
    Bombyx mori
  • 标记方式：
    Non-conjugated

    本页面中的产品，Prothoracicotropic hormone Antibody (CSB-PA324609LA01BTT)，的标记方式是Non-conjugated。对于Prothoracicotropic hormone Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA324609LB01BTT Prothoracicotropic hormone Antibody, HRP conjugated ELISA
    FITC CSB-PA324609LC01BTT Prothoracicotropic hormone Antibody, FITC conjugated
    Biotin CSB-PA324609LD01BTT Prothoracicotropic hormone Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    PTTH is a brain secretory polypeptide of insects which stimulates the prothoracic glands to produce and release ecdysone, the steroid essential to insect development.; Peptides P2K and P6K are presumed to be cleaved post-translationally and may play some unknown physiologically or developmentally important functions.
  • 基因功能参考文献：
    1. HR38 is a prothoracicotropic hormone(PTTH)-stimulated immediate early gene that is, at least in part, induced through Ca(2+)/ERK and PI3K signaling. The present study proposes a potential cross talk mechanism between PTTH and ecdysone signaling to regulate insect development and lays a foundation for a better understanding of the mechanisms of PTTH's actions. PMID: 27090809
    2. There are interconnections among Ca(2+) signaling, adenosine 5'-monophosphate-activated protein kinase, and 4E-BP phosphorylation in in prothoracicotropic hormone (PTTH-activated prothoracic glands of Bombyx mori. PMID: 27751888
    3. Study reports the physical basis of neurohormone PTTH sensing by the receptor tyrosine kinase Torso. Hormone binding by Torso is asymmetric and anticooperative, allowing receptor levels to determine the nature of signal transduction. PMID: 26698662
    4. To examine the expression of Rab proteins and neuropeptide hormones in the brain of the silkworm, Bombyx mori.The Rab1 co-localized with prothoracicotropic hormone. PMID: 22922733
    5. PTTH/PI3K/TOR/4E-BP (S6K) signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands. PMID: 22227406
    6. The s showed that Bombyx mori prothoracicotropic hormone (PTTH)-stimulated ecdysteroidogenesis was partially blocked by LY294002 and wortmannin, indicating that phosphoinositide 3-kinase (PI3K) is involved in PTTH-stimulated ecdysteroidogenesis. PMID: 21199670
    7. Study showed that prothoracicotropic hormone (PTTH) stimulates a rapid increase in tyrosine phosphorylation of at least 2 proteins in prothoracic glands: extracellular signal-regulated kinase and a 120-kDa protein. PMID: 20568296
    8. the TATA box is involved in regulation of PTTH gene expression in B. mori PMID: 20563654
    9. PTTH-stimulated ERK phosphorylation is only partially Ca(2+)- and calmodulin-dependent, and HNMPA-(AM)(3)-sensitive receptor tyrosine kinase is involved in activation of ERK phosphorylation by PTTH. PMID: 19800889

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  • 组织特异性：
    PTTH is synthesized by two dorsolateral neurosecretory cells of the Bombyx brain.
  • 数据库链接：

    KEGG: bmor:692767

    UniGene: Bmo.125