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PCYT2 Antibody

  • 货号：
    CSB-PA017656GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q99447
  • 基因名：
    PCYT2
  • 别名：
    CTP:phosphoethanolamine cytidylyltransferase antibody; ET antibody; Ethanolamine-phosphate cytidylyltransferase antibody; Ethanolaminephosphate Cytidyltransferase antibody; PCY2 antibody; PCY2_HUMAN antibody; Pcyt2 antibody; Phosphate cytidylyltransferase 2 ethanolamine antibody; Phosphorylethanolamine transferase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PCYT2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway. Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally stabilizing membrane-anchored proteins, and participates in important cellular processes such as cell division, cell fusion, blood coagulation, and apoptosis.
  • 基因功能参考文献：
    1. These results suggest that the N-terminal CT domain of hECT contributes to its catalytic reaction, but C-terminal CT domain does not. PMID: 24802409
    2. differences in phosphorylation between Pcyt2 isoforms PMID: 24519946
    3. Pcyt2 expression is responsive to tumor nutritional micro-environment, up-regulated in response to metabolic stress under conditions of serum deprivation. PMID: 22339418
    4. The Pcyt2 promoter is driven by a functional CAAT box (-90/-73) and by negative (-385/-255) and positive regulatory elements (-255/-153) in the upstream regions. PMID: 16023412
    5. EGR1 is an important transcriptional stimulator of the human PCYT2 and that conditions that modify EGR1 also affect the function of ECT and consequently PE synthesis PMID: 18583706

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  • 蛋白家族：
    Cytidylyltransferase family
  • 组织特异性：
    Strongest expression in liver, heart, and skeletal muscle.
  • 数据库链接：

    HGNC: 8756

    OMIM: 602679

    KEGG: hsa:5833

    STRING: 9606.ENSP00000442050

    UniGene: Hs.569843