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PARD6G Antibody

  • 货号:
    CSB-PA863155LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Immunofluorescent analysis of Hela cells using CSB-PA863155LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, SY5Y whole cell lysate, 293 whole cell lysate, PC-3 whole cell lysate, MCF-7 whole cell lysate, A549 whole cell lysate, JK whole cell lysate
      All lanes: PARD6G antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 41, 13 kDa
      Observed band size: 41 kDa
  • 其他:

产品详情

  • 产品描述:

    CUSABIO produces the PARD6G antibody by immunizing rabbits with the recombinant human PARD6G protein (249-326AA). The resulting antibody is a polyclonal antibody and occurs as an unconjugated IgG. Its purity is greater than 95% using protein G purified. It is reactive with human and mouse PARD6G protein. The target protein PARD6G is a component of the mother centriole and controls centrosomal protein in composition through a Par6α-dependent pathway. This PARD6G antibody can be applied in ELISA, WB, and IF analyses.

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) PARD6G Polyclonal antibody
  • Uniprot No.:
    Q9BYG4
  • 基因名:
  • 别名:
    PARD6G antibody; PAR6G antibody; Partitioning defective 6 homolog gamma antibody; PAR-6 gamma antibody; PAR6D antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Partitioning defective 6 homolog gamma protein (249-326AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,PARD6G Antibody (CSB-PA863155LA01HU),的标记方式是Non-conjugated。对于PARD6G Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA863155LB01HU PARD6G Antibody, HRP conjugated ELISA
    FITC CSB-PA863155LC01HU PARD6G Antibody, FITC conjugated
    Biotin CSB-PA863155LD01HU PARD6G Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, WB, IF
  • 推荐稀释比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
  • 基因功能参考文献:
    1. This paper shows Par6G as a negative regulator of the phosphatidylinositol 3'-kinase/phosphoinositide-dependent protein kinase 1/Akt pathway and epithelial cell proliferation and evidence for frequent inactivation of Par6G gene in epithelial cancers. PMID: 26073086
    2. this study is the first to identify Par6gamma as a component of the mother centriole and to report a role of a mother centriole protein in the regulation of centrosomal protein composition. PMID: 23264737
  • 亚细胞定位:
    Cytoplasm. Cell membrane. Cell junction, tight junction.
  • 蛋白家族:
    PAR6 family
  • 组织特异性:
    Widely expressed, with a higher expression in fetal and adult kidney.
  • 数据库链接:

    HGNC: 16076

    OMIM: 608976

    KEGG: hsa:84552

    STRING: 9606.ENSP00000343144

    UniGene: Hs.654920