PAG 1 Antibody

Datasheet

产品详情

产品描述：

CUSABIO uses a partial recombinant protein mapping within 54-380 amino acids of the human PAG 1 protein to immunize the rabbit to produce the anti-PAG 1 polyclonal antibody. This PAG 1 antibody exists as the unconjugated IgG isoform. The purity of this antibody is 95%⁺ using protein G affinity chromatography. This PAG 1 antibody shows reactivity to bovine, human, and rat samples. And it has been validated for use in ELISA and WB applications.

Its target protein PAG 1 is a protein primarily found in the placenta of ruminants (such as cows, sheep, and goats) during pregnancy. PAG 1 plays a role in the formation and maintenance of the placenta. It is also used as a biomarker for pregnancy diagnosis and to monitor fetal growth in ruminant animals.
产品名称：

Rabbit anti-Bovine N/A Polyclonal antibody
Uniprot No.：

Q29432
基因名：

N/A
别名：

Pregnancy-associated glycoprotein 1 antibody; PAG 1 antibody; EC 3.4.23.- antibody; Pregnancy-specific protein B antibody; PSP-B antibody
宿主：

Rabbit
反应种属：

Bovine, Human, Rat
免疫原：

Recombinant Bovine Pregnancy-associated glycoprotein 1 protein (54-380AA)
免疫原种属：

Bovine

标记方式：

Non-conjugated

本页面中的产品，PAG 1 Antibody (CSB-PA644917LA01BO)，的标记方式是Non-conjugated。对于PAG 1 Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA644917LB01BO	PAG 1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA644917LC01BO	PAG 1 Antibody, FITC conjugated
Biotin	CSB-PA644917LD01BO	PAG 1 Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, WB

推荐稀释比：

Application	Recommended Dilution
WB	1:500-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

功能：

Appears to be proteolytically inactive.
基因功能参考文献：
1. This study examines expression patterns of the genes SERPINA14, PAG, and PAG2 at the fetal-maternal interface in dairy heifers experimentally infected with N caninum during the second trimester of pregnancy, when most abortions takes place in natural conditions. PMID: 27045629
2. The clinical implications of these findings are that following infection with N. caninum, most cows will experience some level of placental damage and that this injury correlates with foetal fluid PAG levels and pH. PMID: 26936628
3. These findings indicate that IFN-gamma production correlates negatively and the production of antibodies against N. caninum is uncorrelated with plasma pregnancy-associated glycoproteins levels. PMID: 24456132
4. Restraint stress for 2 h during early pregnancy in heifers increased blood cortisol, but it did not affect the concentrations of progesterone and PAG-1 between days 30 to 40 of gestation. PMID: 21872319
亚细胞定位：

Secreted, extracellular space.
蛋白家族：

Peptidase A1 family
组织特异性：

Trophoblast and placental tissue. Produced specifically in the invasive binucleate cells of the placenta. Becomes detectable in maternal serum soon after implantation.
数据库链接：

KEGG: bta:281964

STRING: 9913.ENSBTAP00000025593

UniGene: Bt.15401