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NDUFS6 Antibody

  • 货号：
    CSB-PA015665DSR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: NDUFS6 antibody at 1.1µg/ml
      Lane 1: Mouse heart tissue
      Lane 2: Mouse kidney tissue
      Lane 3: MCF-7 whole cell lysate
      Lane 4: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 14 kDa
      Observed band size: 14 kDa
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA015665DSR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA015665DSR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) NDUFS6 Polyclonal antibody
  • Uniprot No.：
    O75380
  • 基因名：
  • 别名：
    BC059730 antibody; CI 13kA antibody; CI 13kD A antibody; CI-13kD-A antibody; CI13KDA antibody; Complex I 13kD A antibody; Complex I 13kDa subunit A antibody; Complex I mitochondrial respiratory chain 13 kD subunit antibody; Complex I-13kD-A antibody; IP13 antibody; MGC107676 antibody; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH coenzyme Q reductase) antibody; NADH dehydrogenase [ubiquinone] iron sulfur protein 6, mitochondrial antibody; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial antibody; NADH ubiquinone oxidoreductase 13 kDa A subunit antibody; NADH-ubiquinone oxidoreductase 13 kDa-A subunit antibody; NADH:ubiquinone oxidoreductase NDUFS6 subunit antibody; NADH:ubiquinone oxidoreductase subunit S6 antibody; Ndufs6 antibody; NDUS6_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial protein (29-124AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • 基因功能参考文献：
    1. CD147 appears to regulate complex I activity and apoptosis in malignant melanoma cells by interacting with mitochondrial NDUFS6. PMID: 25470292
    2. NDUFS6, a complex I subunit gene not previously associated with complex I deficiency, was grossly underexpressed in t patient cell lines. PMID: 15372108
    3. NDUFS6 is required for the assembly and stabilization of a portion of complex I that contains a number of subunits. PMID: 17438127
  • 相关疾病：
    Mitochondrial complex I deficiency (MT-C1D)
  • 亚细胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    Complex I NDUFS6 subunit family
  • 数据库链接：

    HGNC: 7713

    OMIM: 252010

    KEGG: hsa:4726

    STRING: 9606.ENSP00000274137

    UniGene: Hs.408257