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MOGS Antibody

  • 货号：
    CSB-PA014713GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q13724
  • 基因名：
  • 别名：
    EC 3.2.1.106 antibody; glucosidase I antibody; Mannosyl oligosaccharide glucosidase antibody; Mannosyl-oligosaccharide glucosidase antibody; Mogs antibody; MOGS_HUMAN antibody; Processing A glucosidase I antibody; Processing A-glucosidase I antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human MOGS
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner.
  • 基因功能参考文献：
    1. A shortened immunoglobulin half-life was determined to be the mechanism underlying the hypogammaglobulinemia in congenital disorder of glycosylation type IIb (CDG-IIb). PMID: 24716661
    2. Perturbation of free oligosaccharide trafficking in endoplasmic reticulum glucosidase I-deficient and castanospermine-treated cells. PMID: 11942856
    3. MafF/NFE2 hetrodimers act as weak transcriptional activators, and, in particular, are able to stimulate activity of the GCS1 promoter. PMID: 12490281
    4. identification of sequence motifs responsible for endoplasmic reticulum localization PMID: 12626409
  • 相关疾病：
    Type IIb congenital disorder of glycosylation (CDGIIb)
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyl hydrolase 63 family
  • 数据库链接：

    HGNC: 24862

    OMIM: 601336

    KEGG: hsa:7841

    STRING: 9606.ENSP00000233616

    UniGene: Hs.516119