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MAP3K13 Antibody

  • 货号：
    CSB-PA108299
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA108299(MAP3K13 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    O43283
  • 基因名：
  • 别名：
    EC 2.7.11.25 antibody; Leucine zipper bearing kinase antibody; Leucine zipper-bearing kinase antibody; LZK antibody; M3K13_HUMAN antibody; MAP3K13 antibody; MEKK13 antibody; MGC133196 antibody; Mitogen activated protein kinase kinase kinase 13 antibody; Mitogen-activated protein kinase kinase kinase 13 antibody; Mixed lineage kinase antibody; MLK antibody; OTTHUMP00000210397 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human MAP3K13
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
  • 基因功能参考文献：
    1. Data indicate that miR-206's effect on Myc was mediated through MAP3K13. PMID: 26918941
    2. Chromosomal localization studies involving FISH mapping demonstrated that the human LZK gene is located at 3q27. PMID: 12186766
  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily
  • 组织特异性：
    Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas.
  • 数据库链接：

    HGNC: 6852

    OMIM: 604915

    KEGG: hsa:9175

    STRING: 9606.ENSP00000265026

    UniGene: Hs.591306