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LRR1 Antibody

  • 货号：
    CSB-PA836247LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA836247LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA836247LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA836247LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) LRR1 Polyclonal antibody
  • Uniprot No.：
    Q96L50
  • 基因名：
    LRR1
  • 别名：
    4 1BB mediated signaling molecule antibody; 4 1BBlrr antibody; 4-1BB-mediated-signaling molecule antibody; 4-1BBlrr antibody; Cyclophilin like 5 antibody; Leucine-rich repeat protein 1 antibody; LLR1_HUMAN antibody; LRR 1 antibody; LRR repeat protein 1 antibody; LRR-1 antibody; LRR-repeat protein 1 antibody; LRR1 antibody; MGC20689 antibody; peptidylprolyl isomerase (cyclophilin) like 5 antibody; Peptidylprolyl isomerase like 5 antibody; Peptidylprolyl isomerase-like 5 antibody; PPIL5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Leucine-rich repeat protein 1 protein (18-159AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，LRR1 Antibody (CSB-PA836247LA01HU)，的标记方式是Non-conjugated。对于LRR1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA836247LB01HU LRR1 Antibody, HRP conjugated ELISA
    FITC CSB-PA836247LC01HU LRR1 Antibody, FITC conjugated
    Biotin CSB-PA836247LD01HU LRR1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • 基因功能参考文献：
    1. Results identify the CRL2(LRR-1) ubiquitin ligase as a conserved regulator of Cip/Kip CKIs that promotes the degradation of C. elegans CKI-1 and human p21. PMID: 21074724
  • 组织特异性：
    Ubiquitous. Maximal expression was seen in the heart and skeletal muscle and minimal expression seen in the kidney.
  • 数据库链接：

    HGNC: 19742

    OMIM: 609193

    KEGG: hsa:122769

    STRING: 9606.ENSP00000298288

    UniGene: Hs.451090