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LRIG2 Antibody

  • 货号：
    CSB-PA013085LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate
      All lanes: LRIG2 antibody at 3.5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 119 kDa
      Observed band size: 119 kDa
    • Immunofluorescence staining of Hela cells with CSB-PA013085LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) LRIG2 Polyclonal antibody
  • Uniprot No.：
    O94898
  • 基因名：
    LRIG2
  • 别名：
    KIAA0806 antibody; Leucine rich repeats and immunoglobulin like domains 2 antibody; Leucine-rich repeats and immunoglobulin-like domains protein 2 antibody; LIG-2 antibody; LIG2 antibody; LRIG2 antibody; LRIG2_HUMAN antibody; UFS2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Leucine-rich repeats and immunoglobulin-like domains protein 2 protein (833-932AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，LRIG2 Antibody (CSB-PA013085LA01HU)，的标记方式是Non-conjugated。对于LRIG2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA013085LB01HU LRIG2 Antibody, HRP conjugated ELISA
    FITC CSB-PA013085LC01HU LRIG2 Antibody, FITC conjugated
    Biotin CSB-PA013085LD01HU LRIG2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Study demonstrated that LRIG2 promoted the PDGFRBinduced proliferation of glioblastoma multiforme cells in vitro and in vivo through regulating the PDGFRB signalingmediated cell cycle progression. PMID: 30015847
    2. Role of LRIG2 in cancer [review] PMID: 27628597
    3. LRIG2 gene is overexpressed in invasive pituitary adenoma. PMID: 21823015
    4. A subset of urofacial syndrome-affected individuals have biallelic mutations in LRIG2 PMID: 23313374
    5. Cytoplasmic expression of LRIG2 is associated with meningiomas. PMID: 22484910
    6. LRIG1 and LRIG2 expressions were seen in precancerous cervical epithelium and found to increase with increasing grade. PMID: 21632100
    7. LRIG2 was found to be a glycoprotein with an molecular weight of 132 kDa, which was encoded by a gene on human chromosome 1p13 and its mRNA was present in all tissues analyzed. PMID: 15145052
    8. LRIG proteins may have a role in epidermal homeostasis and psoriasis PMID: 18037903
    9. This is the first report of an LRIG protein showing a negative effect on survival, suggesting that LRIG2 might have a function different from that of LRIG1, and possibly contributing to the etiology of oligodendroglioma. PMID: 18992012

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  • 相关疾病：
    Urofacial syndrome 2 (UFS2)
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Cytoplasm.
  • 组织特异性：
    Detected in all tissues analyzed.
  • 数据库链接：

    HGNC: 20889

    OMIM: 608869

    KEGG: hsa:9860

    STRING: 9606.ENSP00000355396

    UniGene: Hs.448972