L1 Antibody
产品详情
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产品描述:
The rabbit anti-human papillomavirus type 18 L1 polyclonal antibody was developed in the rabbit using the recombinant HPV18 major capsid protein L1 protein (1-568aa) as the immunogen. After immunization, the rabbit anti-serum was collected and then purified via protein G affinity chromatograph to obtain the high purity HPV18 L1 polyclonal antibody. Its purity is above 95%.
This HPV18 L1 polyclonal antibody can detect the HPV18 major capsid protein L1. And it has been quality validated for ELISA. It may help to study the roles of the HPV18 major capsid protein L1 in the HPV18 infection-associated research.
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产品名称:Rabbit anti-Human papillomavirus type 18 L1 Polyclonal antibody
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Uniprot No.:P06794
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基因名:L1
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别名:L1 antibody; Major capsid protein L1 antibody
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宿主:Rabbit
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反应种属:Human papillomavirus type 18
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免疫原:Recombinant HPV18 Major capsid protein L1 protein (1-568AA)
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免疫原种属:Human papillomavirus type 18
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标记方式:Non-conjugated
本页面中的产品,L1 Antibody (CSB-PA08359A0Rb),的标记方式是Non-conjugated。对于L1 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
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基因功能参考文献:
- L1 sequences were strongly methylated in all cervical carcinomas studied; hypothesize that L1 is preferentially methylated after integration of the HPV genome into the cellular DNA PMID: 16472835
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亚细胞定位:Virion. Host nucleus.
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蛋白家族:Papillomaviridae L1 protein family
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数据库链接:
KEGG: vg:1489090
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