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KCNA7 Antibody

  • 货号：
    CSB-PA847218LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA847218LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) KCNA7 Polyclonal antibody
  • Uniprot No.：
    Q96RP8
  • 基因名：
    KCNA7
  • 别名：
    KCNA7; Potassium voltage-gated channel subfamily A member 7; Voltage-gated potassium channel subunit Kv1.7
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Potassium voltage-gated channel subfamily A member 7 protein (1-143AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，KCNA7 Antibody (CSB-PA847218LA01HU)，的标记方式是Non-conjugated。对于KCNA7 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA847218LB01HU KCNA7 Antibody, HRP conjugated ELISA
    FITC CSB-PA847218LC01HU KCNA7 Antibody, FITC conjugated
    Biotin CSB-PA847218LD01HU KCNA7 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • 基因功能参考文献：
    1. For FOXK1 and KCNA7, the age effect on the sperm epigenome was replicated in an independent cohort of 188 sperm samples. PMID: 28171595
    2. The s conclude that K(v) 1.7 contributes to the membrane-repolarizing current of beta cells during glucose-stimulated insulin. PMID: 22438204
    3. Expressed in heart, but not the cause of progressive familial heart block I. PMID: 11896454
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Potassium channel family, A (Shaker) (TC 1.A.1.2) subfamily, Kv1.7/KCNA7 sub-subfamily
  • 组织特异性：
    Highly expressed in skeletal muscle, heart and kidney.
  • 数据库链接：

    HGNC: 6226

    OMIM: 176268

    KEGG: hsa:3743

    STRING: 9606.ENSP00000221444

    UniGene: Hs.306973