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HSPA14 Antibody

  • 货号：
    CSB-PA020265
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q0VDF9
  • 基因名：
    HSPA14
  • 别名：
    Heat shock 70 kDa protein 14 antibody; Heat shock 70kDa protein 14 antibody; Heat shock protein HSP60 antibody; Heat shock protein hsp70 related protein antibody; HSP60 antibody; HSP70 4 antibody; HSP70 like protein 1 antibody; HSP70-like protein 1 antibody; HSP70L1 antibody; HSP7E_HUMAN antibody; HSPA 14 antibody; HSPA14 antibody; MGC131990 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human HSP60.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
  • 基因功能参考文献：
    1. TLR4 is a key receptor mediating the interaction of Hsp70L1 with DCs and subsequently enhancing the induction of Th1 immune response by Hsp70L1/antigen fusion protein PMID: 21730052
    2. a novel pathway (NBS1-HSF4b-HSPA4/HSPA14 axis) to induce migration, invasion, and transformation, suggesting the activation of multiple signaling events induced by NBS1 overexpression PMID: 21208456
    3. results demonstrate that Hsp70L1 has enhanced Th1 polarizing and adjuvant properties, which appear to be mediated via activation of dendritic cells PMID: 14592822
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Heat shock protein 70 family
  • 数据库链接：

    HGNC: 29526

    OMIM: 610369

    KEGG: hsa:51182

    STRING: 9606.ENSP00000367623

    UniGene: Hs.534169