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HOXD9 Antibody

  • 中文名称：
    HOXD9兔多克隆抗体
  • 货号：
    CSB-PA010689LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA010689LA01HU at dilution of 1:100
    • Western Blot
      Positive WB detected in: Mouse lung tissue
      All lanes: HOXD9 antibody at 3.2μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 37 kDa
      Observed band size: 37 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HOXD9 Polyclonal antibody
  • Uniprot No.：
    P28356
  • 基因名：
    HOXD9
  • 别名：
    homeobox D9 antibody; Homeobox protein Hox D9 antibody; Homeobox protein Hox-4C antibody; Homeobox protein Hox-5.2 antibody; Homeobox protein Hox-D9 antibody; Hox 4.3 antibody; Hox 5.2 antibody; HOX4 antibody; HOX4C antibody; HOXD9 antibody; HXD9_HUMAN antibody; RP23 313J15.10 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Homeobox protein Hox-D9 protein (38-276AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，HOXD9 Antibody (CSB-PA010689LA01HU)，的标记方式是Non-conjugated。对于HOXD9 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA010689LB01HU HOXD9 Antibody, HRP conjugated ELISA
    FITC CSB-PA010689LC01HU HOXD9 Antibody, FITC conjugated
    Biotin CSB-PA010689LD01HU HOXD9 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:2000-1:10000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 基因功能参考文献：
    1. HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma PMID: 26514226
    2. HoxD9 expression is regulated by histone acetylation in endothelial progenitor cells PMID: 25826494
    3. Data show that overexpressing homeobox D9 protein HOXD9 in mucinous ovarian carcinomas (MOCs)cells augmented the neoplastic phenotype PMID: 26075790
    4. The study investigates the temperature dependence of the internal motions of the lysine side-chain NH3(+) groups that form ion pairs with DNA phosphate groups in the HoxD9 homeodomain-DNA complex. PMID: 25489884
    5. Results show that melanoma patients with HOXD9 hypermethylation in lymph node metastasis had poorer disease-free and overall survival. PMID: 24014427
    6. A genome-wide array-comparative genomic hybridization (aCGH) analysis revealed global chromosomal aberration in MWCNTs-treated clones, predominantly at chromosome 2q31-32, where the potential oncogenes HOXD9 and HOXD13 are located PMID: 23984819
    7. The association between SNP of the HOXD9 gene and developmental hip dysplasia reached significance in Chinese Han females. PMID: 22520331
    8. Our results suggest that HOXD9 may be a novel marker of GCSCs and cell proliferation and/or survival factor in gliomas and glioma cancer stem-like cells, and a potential therapeutic target. PMID: 21600039
    9. 117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly PMID: 11778160
    10. findings not only indicate that the HOXD9 gene is exclusively expressed in the rheumatoid arthritis synovium but also suggest that the HOXD9 gene contributes to the pathology of rheumatoid arthritis through the fibroblast-like synoviocytes PMID: 12060849
    11. HoxD9 and Pbx1 are inappropriately expressed in most human esophageal squamous cell carcinoma. Understanding the role of Hox genes in esophageal epithelial cell carcinogenesis may not only augment early detection but also offer possiblde treatment. PMID: 15770739

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Abd-B homeobox family
  • 数据库链接：

    HGNC: 5140

    OMIM: 142982

    KEGG: hsa:3235

    STRING: 9606.ENSP00000249499

    UniGene: Hs.236646