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HERC3 Antibody

  • 货号：
    CSB-PA618972LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HERC3 Polyclonal antibody
  • Uniprot No.：
    Q15034
  • 基因名：
  • 别名：
    HERC3 antibody; KIAA0032Probable E3 ubiquitin-protein ligase HERC3 antibody; EC 2.3.2.26 antibody; HECT domain and RCC1-like domain-containing protein 3 antibody; HECT-type E3 ubiquitin transferase HERC3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Probable E3 ubiquitin-protein ligase HERC3 protein (1-200AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，HERC3 Antibody (CSB-PA618972LA01HU)，的标记方式是Non-conjugated。对于HERC3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA618972LB01HU HERC3 Antibody, HRP conjugated ELISA
    FITC CSB-PA618972LC01HU HERC3 Antibody, FITC conjugated
    Biotin CSB-PA618972LD01HU HERC3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
  • 基因功能参考文献：
    1. HERC3 negatively regulates NF-kappaB signaling by enhancing RelA subunit degradation. PMID: 26476452
    2. we found somatic mutations of HERC2, HERC3, TRIP12, UBE2Q1 and UBE4B genes in gastric carcinoma and colorectal carcinomas with microsatellite instability PMID: 22124266
  • 亚细胞定位：
    Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.
  • 数据库链接：

    HGNC: 4876

    OMIM: 605200

    KEGG: hsa:8916

    STRING: 9606.ENSP00000264345

    UniGene: Hs.35804