Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. GRAMD4 Antibody

GRAMD4 Antibody

  • 货号：
    CSB-PA764225LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse brain tissue
      All lanes: GRAMD4 antibody at 3.4µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 67, 11 kDa
      Observed band size: 67 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA764225LA01HU at dilution of 1:100
    • Western Blot
      Positive WB detected in: MCF-7 whole cell lysate
      All lanes: GRAMD4 antibody at 5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 67, 11 kDa
      Observed band size: 67 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GRAMD4 Polyclonal antibody
  • Uniprot No.：
    Q6IC98
  • 基因名：
    GRAMD4
  • 别名：
    GRAMD4; DIP; KIAA0767; GRAM domain-containing protein 4; Death-inducing protein
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human GRAM domain-containing protein 4 protein (23-161AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GRAMD4 Antibody (CSB-PA764225LA01HU)，的标记方式是Non-conjugated。对于GRAMD4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA764225LB01HU GRAMD4 Antibody, HRP conjugated ELISA
    FITC CSB-PA764225LC01HU GRAMD4 Antibody, FITC conjugated
    Biotin CSB-PA764225LD01HU GRAMD4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response.
  • 基因功能参考文献：
    1. The expression of GRAMD4 is up-regulated in hepatocellular carcinoma cell(HCC cell) lines and HCC tissues, and the increased expression is correlated with the clinicopathological characteristics of HCC. PMID: 23388340
    2. GRAMD4 induces changes in Bcl-2 and Bax protein levels PMID: 21127500
    3. localizes to the mitochondria, upregulated following E2F1 induction PMID: 15565177
    4. DIP induces p53-independent caspase-dependent and -independent apoptosis. DIP is localized in the mitochondria. DIP accumulates upon E2F1 activation. PMID: 15565177
  • 亚细胞定位：
    Mitochondrion membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 组织特异性：
    Expressed in lung and in primary lung squamous cell carcinoma (LSCC).
  • 数据库链接：

    HGNC: 29113

    OMIM: 613691

    KEGG: hsa:23151

    STRING: 9606.ENSP00000354313

    UniGene: Hs.475150