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  4. GPR116 Antibody

GPR116 Antibody

  • 货号：
    CSB-PA008223
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q8IZF2
  • 基因名：
  • 别名：
    DKFZp564O1923 antibody; FLJ90640 antibody; G protein coupled receptor 116 antibody; GP116_HUMAN antibody; GPR116 antibody; Ig Hepta homolog antibody; KIAA0758 antibody; KPG_001 antibody; OTTHUMP00000016557 antibody; Probable G protein coupled receptor 116 antibody; Probable G-protein coupled receptor 116 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human GPR116.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Receptor that plays a critical role in lung surfactant homeostasis. May play a role in controlling adipocyte function.
  • 基因功能参考文献：
    1. our study demonstrated that GPR116 was significantly upregulated in CRC tissues and could serve as an independent prognostic indicator for patients with CRC. PMID: 28624786
    2. These findings show that GPR116 is crucial for the metastasis of breast cancer and support GPR116 as a potential prognostic marker and drug target against metastatic human breast cancer. PMID: 24008316
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    4. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
    5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    6. SEA domain autoproteolysis accelerated by conformational strain. PMID: 18308334
    7. SEA domain autoproteolysis accelerated by conformational strain: mechanistic aspects. PMID: 18314133
    8. Clinical trial and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 18519826

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  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
  • 数据库链接：

    HGNC: 19030

    KEGG: hsa:221395

    STRING: 9606.ENSP00000265417

    UniGene: Hs.362806