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FAM19A4 Antibody

  • 货号：
    CSB-PA836253LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FAM19A4 Polyclonal antibody
  • Uniprot No.：
    Q96LR4
  • 基因名：
    FAM19A4
  • 别名：
    TAFA4 antibody; FAM19A4 antibody; Chemokine-like protein TAFA-4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein FAM19A4 protein (36-140AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，FAM19A4 Antibody (CSB-PA836253LA01HU)，的标记方式是Non-conjugated。对于FAM19A4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA836253LB01HU FAM19A4 Antibody, HRP conjugated ELISA
    FITC CSB-PA836253LC01HU FAM19A4 Antibody, FITC conjugated
    Biotin CSB-PA836253LD01HU FAM19A4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Modulates injury-induced and chemical pain hypersensitivity. Ligand of FPR1, can chemoattract macrophages, promote phagocytosis and increase ROS release.
  • 基因功能参考文献：
    1. Hypermethylation of FAM19A4/miR124-2 in the self-sample was tested in a quantitative methylation specific PCR and compared between lesions caused by HPV16/18 and other hrHPV genotypes. There were no differences in the percentages of positive FAM19A4/miR124-2 methylation assays between lesions caused by HPV16/18 (73.8% in CIN3+) or other hrHPV genotypes (66.7% in CIN3+) (p=0.538). PMID: 30219239
    2. With a similarly good clinical performance in both sample types, combined FAM19A4 methylation analysis and HPV16/18 genotyping provides a feasible triage strategy for hrHPV-positive women, with direct applicability on self-samples PMID: 27415009
    3. FAM19A4/mir124-2 methylation analysis performs equally well in HPV-positive lavage- and brush self-samples to identify women with CIN3+. In combination with HPV16/18 genotyping, significantly higher CIN3+ sensitivities are obtained, at decreased specificity. PMID: 26921784
    4. FAM19A4 is a novel ligand of formyl peptide receptor 1. PMID: 25109685
    5. among high risk HPV-positive women from an outpatient population aged >/= 30 years, methylation analysis of FAM19A4 is an attractive marker for the identification of women with high-grade cervical intraepithelial neoplasia and cervical cancer PMID: 26317579
    6. High methylation of FAM19A4 is associated with cervical carcinomas. PMID: 25281488

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    FAM19/TAFA family
  • 组织特异性：
    Expressed in brain. Expressed in LPS-stimulated monocytes and macrophages, especially in polarized M1.
  • 数据库链接：

    HGNC: 21591

    OMIM: 617498

    KEGG: hsa:151647

    STRING: 9606.ENSP00000295569

    UniGene: Hs.187873