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EPGN Antibody

  • 货号：
    CSB-PA006336
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 293T cells using Epigen Polyclonal Antibody
    • Western Blot analysis of 293T 823 cells using Epigen Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q6UW88
  • 基因名：
    EPGN
  • 别名：
    ALGV3072 antibody; EPG antibody; EPGN antibody; EPGN_HUMAN antibody; Epigen antibody; Epigen precursor antibody; Epithelial mitogen antibody; PRO9904 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Epigen.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
  • 基因功能参考文献：
    1. Study shows how the EGFR ligands epiregulin (EREG) and epigen (EPGN) stabilize different dimeric conformations of the EGFR extracellular region. Results reveal how responses to different EGFR ligands are defined by receptor dimerization strength and signaling dynamics. These findings have broad implications for understanding receptor tyrosine kinase (RTK) signaling specificity. PMID: 28988771
    2. cloning of a related gene in mouse PMID: 112783
    3. EPG is an EGF-like growth factor and a low affinity ligand PMID: 15611079
  • 亚细胞定位：
    [Isoform 1]: Membrane; Single-pass type I membrane protein.; [Isoform 2]: Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.; [Isoform 6]: Secreted.
  • 数据库链接：

    HGNC: 17470

    KEGG: hsa:255324

    UniGene: Hs.401237