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EFS Antibody

  • 货号：
    CSB-PA007470GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O43281
  • 基因名：
    EFS
  • 别名：
    EFS antibody; CASS3Embryonal Fyn-associated substrate antibody; hEFS antibody; Cas scaffolding protein family member 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human EFS
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
  • 基因功能参考文献：
    1. EFS and CASS4 protein function in the context of the larger CAS family group. [Review] PMID: 26119091
    2. we suggest that EFS should be considered as a novel tumor suppressor gene in prostate cancer. PMID: 25296736
    3. Analysis of 16 Uveal melanoma showed full methylation of the EFS CpG island in 8 (50%), no methylation in 5(31%)and partial methylation in 3 (19%)tumors. Kaplan-Meier analysis revealed higher risk of metastatic progression for tumors with EFS methylation. PMID: 21871071
  • 蛋白家族：
    CAS family
  • 组织特异性：
    The protein has been detected in lung and placenta.
  • 数据库链接：

    HGNC: 16898

    OMIM: 609906

    KEGG: hsa:10278

    STRING: 9606.ENSP00000216733

    UniGene: Hs.24587