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DAP3 Antibody

  • 货号：
    CSB-PA006497ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: 28S ribosomal protein S29, mitochondrial antibody at 10μg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 46, 42 kDa
      Observed band size: 46 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA006497ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DAP3 Polyclonal antibody
  • Uniprot No.：
    P51398
  • 基因名：
    DAP3
  • 别名：
    28S ribosomal protein S29 antibody; 28S ribosomal protein S29 mitochondrial antibody; bMRP10 antibody; DAP 3 antibody; DAP-3 antibody; Dap3 antibody; Death associated protein 3 antibody; Death-associated protein 3 antibody; DKFZp686G12159 antibody; FLJ12817 antibody; Ionizing radiation resistance conferring protein antibody; MGC126058 antibody; MGC126059 antibody; Mitochondrial 28S ribosomal protein S29 antibody; mitochondrial antibody; MITOCHONDRIAL RIBOSOMAL PROTEIN S29 antibody; MRP S29 antibody; MRP-S29 antibody; MRPS29 antibody; OTTHUMP00000033480 antibody; OTTHUMP00000033481 antibody; PSD-95/SAP90-binding protein 3 antibody; RT29_HUMAN antibody; S29mt antibody; SAP90/PSD-95-associated protein 3 antibody; SAPAP3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human 28S ribosomal protein S29, mitochondrial protein (159-398AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in mediating interferon-gamma-induced cell death.
  • 基因功能参考文献：
    1. DAP3 plays important roles in mitochondrial function and dynamics PMID: 26306039
    2. DAP3 silencing contributes to breast carcinogenesis. PMID: 25738636
    3. Knockdown of DAP3 expression promoted cell migration. PMID: 24300973
    4. Study demonstrates an inverse association between DAP3 mRNA levels and tumour stage and clinical outcome in breast cancer. PMID: 22287761
    5. identified a novel DAP3-binding protein termed death ligand signal enhancer (DELE); results demonstrated the biological significance of DELE for apoptosis signal mediated by death receptors PMID: 20563667
    6. show that interferon-beta promoter stimulator 1 (IPS-1) binds DAP3 and induces anoikis by caspase activation. PMID: 19644511
    7. Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor PMID: 12099703
    8. not involved in TRAIL-induced apoptosis PMID: 12359235
    9. DAP3 has a role in the molecular pathway that culminates in fragmented mitochondria PMID: 15175341
    10. DAP3 gene might be associated with the mechanisms responsible for adult bronchial asthma and contribute to airway inflammation and remodeling PMID: 15179560
    11. DAP3 has a role in anoikis signaling and in apoptosis induction caused by cell detachment PMID: 15302871
    12. High DAP3 expression is correlated with thymoma stage PMID: 15679048
    13. study investigated the phosphorylation status of ribosomal DAP3 and mapped the phosphorylation sites by tandem mass spectrometry PMID: 18227431
    14. Complex I and DAP3, hNOA1 may play a role in mitochondrial respiration and apoptosis. PMID: 19103604
    15. DAP3 may participate in mitochondrial maintenance and play a role in the balance between mitochondrial homoeostasis and tumourigenesis in thyroid oncocytic tumors. PMID: 19536094

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  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Mitochondrion-specific ribosomal protein mS29 family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 2673

    OMIM: 602074

    KEGG: hsa:7818

    STRING: 9606.ENSP00000341692

    UniGene: Hs.516746