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CLGN Antibody

  • 货号：
    CSB-PA005544LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: CLGN antibody at 7µg/ml
      Lane 1: Mouse brain tissue
      Lane 2: Mouse lung tissue
      Lane 3: Jurkat whole cell lysate
      Lane 4: HepG2 whole cell lysate
      Lane 5: PC-3 whole cell lysate
      Lane 6: Hela whole cell lysate
      Lane 7: HL60 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 71, 47 kDa
      Observed band size: 80 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA005544LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA005544LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CLGN Polyclonal antibody
  • Uniprot No.：
    O14967
  • 基因名：
    CLGN
  • 别名：
    CLGN; Calmegin
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Calmegin protein (200-400AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CLGN Antibody (CSB-PA005544LA01HU)，的标记方式是Non-conjugated。对于CLGN Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA005544LB01HU CLGN Antibody, HRP conjugated ELISA
    FITC CSB-PA005544LC01HU CLGN Antibody, FITC conjugated
    Biotin CSB-PA005544LD01HU CLGN Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions.
  • 基因功能参考文献：
    1. In gene-based analysis CLGN1 represented one of a cluster of genes, which interacted with sodium to influence Blood Pressure. PMID: 27271309
    2. Although their similarity in carbohydrate binding specificities is high, there seems to be some differences in the mode of substrate recognition between calmegin and calnexin. PMID: 24769397
    3. calmegin expression is regulated by histone deacetylase and CpG methyltransferase in a coordinative way PMID: 16264275
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Calreticulin family
  • 组织特异性：
    Detected in testis (at protein level). Detected in testis.
  • 数据库链接：

    HGNC: 2060

    OMIM: 601858

    KEGG: hsa:1047

    STRING: 9606.ENSP00000326699

    UniGene: Hs.86368